Full Product Name
AFF2 Antibody
Product Synonym Names
AF4/FMR2 family member 2; Fragile X E mental retardation syndrome protein; Fragile X mental retardation 2 protein; FMR2P; Protein FMR-2; Protein Ox19; AFF2; FMR2; OX19
Product Gene Name
anti-AFF2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P51816
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human AF4/FMR2 family member 2 protein (575-705AA)
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-AFF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AFF2 antibody
RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure.
Product Categories/Family for anti-AFF2 antibody
Neuroscience
Applications Tested/Suitable for anti-AFF2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-AFF2 antibody
WB: 1:500-1:5000
Western Blot (WB) of anti-AFF2 antibody
Western Blot
Positive WB detected in: A549 whole cell lysate
All lanes: AFF2 antibody at 5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 145, 141, 48, 144, 106 KDa
Observed band size: 145 KDa
NCBI/Uniprot data below describe general gene information for AFF2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001162593.1
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NCBI GenBank Nucleotide #
NM_001169122.1
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UniProt Primary Accession #
P51816
[Other Products]
UniProt Secondary Accession #
O43786; O60215; P78407; Q13521; Q14323; Q7Z2F7; A2RTY4; B4DXD5; B7WNQ1; B7ZLD6; B7ZLD9[Other Products]
UniProt Related Accession #
P51816[Other Products]
Molecular Weight
105,116 Da
NCBI Official Full Name
AF4/FMR2 family member 2 isoform 2
NCBI Official Synonym Full Names
AF4/FMR2 family member 2
NCBI Official Symbol
AFF2??[Similar Products]
NCBI Official Synonym Symbols
FMR2; MRX2; OX19; FMR2P; FRAXE
??[Similar Products]
NCBI Protein Information
AF4/FMR2 family member 2
UniProt Protein Name
AF4/FMR2 family member 2
UniProt Synonym Protein Names
Fragile X E mental retardation syndrome protein; Fragile X mental retardation 2 protein; FMR2P; Protein FMR-2; Protein Ox19
Protein Family
AF4/FMR2 family
UniProt Gene Name
AFF2??[Similar Products]
UniProt Synonym Gene Names
FMR2; OX19; FMR2P; Protein FMR-2??[Similar Products]
NCBI Summary for AFF2
This gene encodes a putative transcriptional activator that is a member of the AF4FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked cognitive disability. In addition, this gene contains 6-25 GCC repeats that are expanded to >200 repeats in the disease state. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jul 2016]
UniProt Comments for AFF2
RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure.
Research Articles on AFF2
1. Partial AFF2 microduplication in a patient with auditory processing disorder, emotional impairment and macrosomia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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