Product Name
Aldehyde dehydrogenase (Aldh3a2), Polyclonal Antibody
Full Product Name
Rabbit anti Saccharomyces cerevisiae Aldehyde dehydrogenase
Product Gene Name
anti-Aldh3a2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 10; NC_005109.3 (47300331..47320877, complement). Location: 10q22
3D Structure
ModBase 3D Structure for P30839
Species Reactivity
Saccharomyces cerevisiae
Specificity
IgG fraction of polyclonal Rabbit antiSerum to aldehyde dehydrogenase from baker's yeast.
Preparation and Storage
Store at 4 degree C.
Other Notes
Small volumes of anti-Aldh3a2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-Aldh3a2 antibody
Bacterial, Fungal, Viral
Applications Tested/Suitable for anti-Aldh3a2 antibody
Indirect Immunofluorescence (IF), ELISA (EIA), Dot Blot (DB), Immunoblotting (IB)
NCBI/Uniprot data below describe general gene information for Aldh3a2. It may not necessarily be applicable to this product.
NCBI Accession #
AAA41555.1
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UniProt Primary Accession #
P30839
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UniProt Related Accession #
P30839[Other Products]
Molecular Weight
54,082 Da[Similar Products]
NCBI Official Full Name
aldehyde dehydrogenase
NCBI Official Synonym Full Names
aldehyde dehydrogenase 3 family, member A2
NCBI Official Symbol
Aldh3a2??[Similar Products]
NCBI Official Synonym Symbols
Aldh4; FALDH
??[Similar Products]
NCBI Protein Information
fatty aldehyde dehydrogenase; msALDH; aldehyde dehydrogenase 4; aldehyde dehydrogenase 3A2; microsomal aldehyde dehydrogenase; aldehyde dehydrogenase family 3 member A2; alcohol dehydrogenase family 3, subfamily A2; aldehyde dehydrogenase family 3, subfamily A2
UniProt Protein Name
Fatty aldehyde dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A2; Microsomal aldehyde dehydrogenase
Protein Family
Aldehyde dehydrogenase
UniProt Gene Name
Aldh3a2??[Similar Products]
UniProt Synonym Gene Names
Aldh4; msALDH??[Similar Products]
UniProt Entry Name
AL3A2_RAT
UniProt Comments for Aldh3a2
ALDH3A2: Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. Defects in ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS). SLS is an autosomal recessive neurocutaneous disorder characterized by a combination of severe mental retardation, spastic di- or tetraplegia and congenital ichthyosis (increased keratinization). Ichthyosis is usually evident at birth, neurologic symptoms appear in the first or second year of life. Most patients have an IQ of less than 60. Additional clinical features include glistening white spots on the retina, seizures, short stature and speech defects. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Endoplasmic reticulum; Mitochondrial; Oxidoreductase; Membrane protein, integral; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Secondary Metabolites Metabolism - limonene and pinene degradation; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - butanoate; Lipid Metabolism - fatty acid; Carbohydrate Metabolism - ascorbate and aldarate; Lipid Metabolism - glycerolipid; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - pyruvate; Other Amino Acids Metabolism - beta-alanine; EC 1.2.1.3; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - lysine degradation
Cellular Component: mitochondrion; intracellular membrane-bound organelle; endoplasmic reticulum; mitochondrial inner membrane; integral to membrane; peroxisome; nucleus; cytosol
Molecular Function: long-chain-alcohol oxidase activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; 3-chloroallyl aldehyde dehydrogenase activity; long-chain-aldehyde dehydrogenase activity
Biological Process: phytol metabolic process; epidermis development; response to reactive oxygen species; central nervous system development; formaldehyde metabolic process; aldehyde metabolic process; sesquiterpenoid metabolic process; peripheral nervous system development
Research Articles on Aldh3a2
1. FALDH has roles in insulin action and is deregulated in states associated with altered insulin signaling
Precautions
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Disclaimer
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