For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

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Small volumes of ALDH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2607350 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Aldehyde dehydrogenase (ALDH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ALDH. The ELISA analytical biochemical technique of the MBS2607350 kit is based on ALDH antibody-ALDH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ALDH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ALDH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

54,082 Da

aldehyde dehydrogenase 3 family, member A2

fatty aldehyde dehydrogenase

Fatty aldehyde dehydrogenase

Aldh4; msALDH??[Similar Products]

AL3A2_RAT

ALDH3A2: Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. Defects in ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS). SLS is an autosomal recessive neurocutaneous disorder characterized by a combination of severe mental retardation, spastic di- or tetraplegia and congenital ichthyosis (increased keratinization). Ichthyosis is usually evident at birth, neurologic symptoms appear in the first or second year of life. Most patients have an IQ of less than 60. Additional clinical features include glistening white spots on the retina, seizures, short stature and speech defects. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; Endoplasmic reticulum; Mitochondrial; Membrane protein, integral; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - lysine degradation; Carbohydrate Metabolism - ascorbate and aldarate; Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - pyruvate; EC 1.2.1.3; Secondary Metabolites Metabolism - limonene and pinene degradation; Lipid Metabolism - glycerolipid; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - histidine; Lipid Metabolism - fatty acid; Carbohydrate Metabolism - propanoate

Cellular Component: cytosol; endoplasmic reticulum; integral to membrane; intracellular membrane-bound organelle; mitochondrial inner membrane; mitochondrion; nucleus; peroxisome

Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; long-chain-alcohol oxidase activity; long-chain-aldehyde dehydrogenase activity

Biological Process: aldehyde metabolic process; central nervous system development; epidermis development; formaldehyde metabolic process; peripheral nervous system development; phytol metabolic process; response to reactive oxygen species; sesquiterpenoid metabolic process

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