Product Name
ENAM, cDNA Clone
Full Product Name
ENAM cDNA Clone
Product Gene Name
ENAM cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgttggtgc ttcggtgcag gcttggaacc tcttttccta aactagataa cttggtacca aaaggcaaaa tgaagattct cctggtcttt ctagggcttc ttggtaattc tgttgctatg ccaatgcaca tgccccgaat gcctggattt agcagtaaaa gtgaggagat gatgcggtat aatcaattca actttatgaa cggcccacat atggcacacc tggggccctt ctttggaaac ggtctccctc agcaatttcc acagtaccag atgcccatgt ggcctcagcc accacccaac acatggcatc cacggaaatc ctcagcaccc aaacgtcata acaagactga tcagacccaa gaaacccaga aacccaacca gactcagtca aaaaagccac cacaaaagcg gcctttgaag cagccatcac ataatcaacc tcagcccgaa gaggaagctc aaccccctca ggcattccca ccatttggaa atgggctatt cccctatcaa caaccaccat ggcaaattcc acagaggtta ccaccaccag gttatggacg cccaccaatc agcaatgaag aaggggggaa tccttacttt ggatattttg gatatcatgg ctttgggggt cgccctcctt attattcaga agaaatgttt gaacaagatt ttgaaaaacc caaagaagaa gatcctccta aagcagaaag tccaggcaca gaacccacag ctaattcaac agtcactgag acgaattcta cccaaccaaa tcctaaaggg agtcagggag gaaatgacac cagccccaca ggaaacagta ccccaggact aaacactggg aacaaccctc cagctcaaaa tgggattggc ccactccctg cagtcaacgc ttcaggccag ggagggccag gaagtcaaat cccatggaga ccaagtcagc caaatattcg tgaaaatcat ccatatccta atataagaaa ttttccttca ggaagacagt ggtatttcac tggtactgtc atggggcaca gacagaatag gcctttttac agaaatcaac aagttcaaag gggtcctcgg tggaacttct ttgcttggga acgtaaacaa gtagctcgtc caggaaatcc agtttatcac aaagcttacc ctcctacttc aagaggcaat tatcccaatt atgcaggaaa tccagcaaat ctcagaagaa agcctcaggg gccaaataaa caccctgtag gaactactgt tgccccactg ggtcccaaac ctggccctgt tgttcgcaat gaaaaaatcc aaaatccaaa ggagaagccc ctgggtccaa aagaacaaat aatagttcct acaaagaatc caaccagccc ctggagaaac tctcaacagt atgaagttaa taaatcaaat tataaactgc ctcactctga gggttatatg ccagtcccaa attttaattc tgttgatcaa catgaaaact cctattaccc aagaggagat tccagaaaag tcccaaattc tgatggacaa acccaaagcc agaatttgcc caaagggatt gttttagggt caagaaggat gccatatgaa tcagaaacta atcagtcaga attaaagcac agctcatatc agcctgctgt ataccctgag gaaatccctt ctcctgcaaa agaacatttt cctgctggaa gaaatacttg ggaccaccaa gaaatctctc caccttttaa ggaagatcca gggaggcaag aagaacattt accccatcct tcccatggtt ctagaggaag tgttttctac cctgaatata acccatatga tcccagggaa aactcaccat accttagagg caatacatgg gatgagagag atgattctcc caatactatg gggcaaaaag aaagtccact ctaccccata aataccccag accagaagga gatagtccct tataatgaag aggacccagt tgatccaact ggagatgaag tctttcctgg acaaaataga tggggtgaag agttgagctt caaaggaggc ccaacagtta ggcactatga aggtgaacaa tatacctcaa atcagccaaa ggaatatctt ccctattctt tagataatcc atcaaaacca agggaggatt tttattacag tgaattttac ccatggagcc cggatgagaa ttttccatca tataatacag cttctactat gccaccacct atagagagca ggggctacta cgttaataat gccgctggac cagaagaaag cactctattt ccttcacgga attcctggga ccacaggata caagcccaag ggcagagaga aagaaggccg tattttaaca gaaatatctg ggatcaggca acacatttac aaaaagcccc agctaggcca ccagaccaga aaggtaacca gccctattac agtaacaccc cagctgggct tcagaaaaat ccaatatggc atgaaggtga gaatttgaac tatggcatgc aaataactag gatgaattct ccagagagag aacattcatc tttccctaac ttcatcccac caagttaccc atcaggtcaa aaagaagcac atttatttca cctaagccag agaggctctt gctgtgctgg tagctccaca gggcccaagg acaatccact agctctacaa gactacactc catcctatgg tcttgcacct ggggagaacc aagacaccag tcctctgtat acagacggta gtcataccaa gcagacaaga gatatcatct ccccaacaag catcctacca ggccaaagaa acagctcaga gaagagggaa agccaaaacc cttttagaga tgatgtgtcc acgctgagga ggaacacacc atgttctata aagaatcaac tgggccaaaa ggaaattatg ccctttcctg aagccagttc ccttcaatca aagaatacac cttgtctcaa aaatgatctt ggaggagatg ggaacaacat tctggaacaa gtttttgaag acaaccagct caatgaaaga actgttgacc ttactcctga gcagcttgtt attggtacac ctgatgaagg ctccaatcca gaaggcatcc aaagtcaagt ccaagaaaat gagagtgaga ggcaacagca aagaccatct aacattctgc atttgccatg ctttggctcc aaattagcaa agcatcactc ttccaccacc ggaactccat ctagcgatgg aaggcaaagc ccatttgatg gggattcaat tacgcctact gaaaatccta acacattggt tgagttagct actgaggaac aatttaagag tataaatgta gacccacttg atgcagatga acacagtcca tttgaattcc ttcaaagagg gaccaatgta caggaccagg tacaagactg cttactactt caggcctag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ENAM cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ENAM. It may not necessarily be applicable to this product.
NCBI Accession #
BC117308
[Other Products]
UniProt Secondary Accession #
Q17RI5; Q9H3D1[Other Products]
UniProt Related Accession #
Q9NRM1[Other Products]
Molecular Weight
128,785 Da
NCBI Official Full Name
Homo sapiens enamelin, mRNA
NCBI Official Synonym Full Names
enamelin
NCBI Official Symbol
ENAM??[Similar Products]
NCBI Official Synonym Symbols
ADAI; AI1C; AIH2
??[Similar Products]
NCBI Protein Information
enamelin
UniProt Protein Name
Enamelin
UniProt Gene Name
ENAM??[Similar Products]
UniProt Entry Name
ENAM_HUMAN
NCBI Summary for ENAM
Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene encodes the largest protein in the enamel matrix of developing teeth. The protein is involved in the mineralization and structural organization of enamel. Defects in this gene result in amelogenesis imperfect type 1C.[provided by RefSeq, Oct 2009]
UniProt Comments for ENAM
enamelin: Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation. Defects in ENAM are the cause of amelogenesis imperfecta type 1B (AI1B). AI1B is an autosomal dominant defect of enamel formation. Clinical manifestations may be variable. Some cases present with generalized enamel hypoplasia resulting in small, smooth, yellow and spaced teeth (smooth hypoplastic AI). Others show horizontal rows of pits, grooves or a hypoplastic area in the enamel (local hypoplastic AI). Defects in ENAM are the cause of amelogenesis imperfecta type 1C (AI1C); also known as amelogenesis imperfecta hypoplastic with or without openbite malocclusion. AI1C is an autosomal recessive defect of dental enamel formation. Teeth show hypoplastic and unmineralized enamel, and a yellow-brown discoloration. Enamel defects can be associated with facial and oral features including vertical dysgnathia and anterior openbite malocclusion.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 4q13.3
Disease: Amelogenesis Imperfecta, Type Ib; Amelogenesis Imperfecta, Type Ic
Research Articles on ENAM
1. Overrepresentation of the G allele of the enamelin marker was seen in the erosion group compared to the unaffected group.
Precautions
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Disclaimer
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