Product Name
RDH5, Blocking Peptide
Full Product Name
RDH5 Peptide - middle region
Product Gene Name
RDH5 blocking peptide
[Similar Products]
Product Synonym Gene Name
RDH1; 9cRDH; SDR9C5; HSD17B9[Similar Products]
RDH5 peptide (MBS3246167) is used for blocking the activity of RDH5 antibody (MBS3221433)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: RGFRVLASCL TPSGAEDLQR VASSRLHTTL LDITDPQSVQ QAAKWVEMHV
3D Structure
ModBase 3D Structure for Q92781
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of RDH5 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
RDH5 blocking peptide
This is a synthetic peptide designed for use in combination with anti- RDH5 Antibody, made
Target Description: This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.
Product Categories/Family for RDH5 blocking peptide
Peptide
NCBI/Uniprot data below describe general gene information for RDH5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001186700.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001199771.1
[Other Products]
UniProt Primary Accession #
Q92781
[Other Products]
UniProt Related Accession #
Q92781[Other Products]
NCBI Official Full Name
11-cis retinol dehydrogenase
NCBI Official Synonym Full Names
retinol dehydrogenase 5
NCBI Official Symbol
RDH5??[Similar Products]
NCBI Official Synonym Symbols
RDH1; 9cRDH; SDR9C5; HSD17B9
??[Similar Products]
NCBI Protein Information
11-cis retinol dehydrogenase
UniProt Protein Name
11-cis retinol dehydrogenase
UniProt Synonym Protein Names
9-cis retinol dehydrogenase; 9cRDH
Protein Family
11-cis retinol dehydrogenase
UniProt Gene Name
RDH5??[Similar Products]
UniProt Synonym Gene Names
RDH1; 11-cis RDH; 11-cis RoDH; 9cRDH??[Similar Products]
UniProt Entry Name
RDH1_HUMAN
NCBI Summary for RDH5
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010]
Research Articles on RDH5
1. T) in exon 4 of the RDH5 gene (MIM: 601617) was identified. This mutation resulted in substitution of phenyl alanine for serine at amino acid 201 (p.Ser201Phe) of the RDH5 gene. Identification of this mutation reveals the allelic heterogeneity of RDH5 in patients with retinitis pigmentosa phenotype.">a novel homozygous missense mutation, (c.602 C > T) in exon 4 of the RDH5 gene (MIM: 601617) was identified. This mutation resulted in substitution of phenyl alanine for serine at amino acid 201 (p.Ser201Phe) of the RDH5 gene. Identification of this mutation reveals the allelic heterogeneity of RDH5 in patients with retinitis pigmentosa phenotype.
Precautions
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Disclaimer
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