Mouse Patatin-like phospholipase domain-containing protein 3 (PNPLA3) ELISA kit; RP4-796I17.1; ADPN; C22orf20; iPLA (2) epsilon; adiponutrin; patatin-like phospholipase domain containing 3

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of PNPLA3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9337027 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the patatin-like phospholipase domain containing 3 (PNPLA3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PNPLA3. The ELISA analytical biochemical technique of the MBS9337027 kit is based on PNPLA3 antibody-PNPLA3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PNPLA3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PNPLA3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

45,772 Da

patatin-like phospholipase domain containing 3

patatin-like phospholipase domain-containing protein 3; adiponutrin; iPLA2-epsilon; acylglycerol O-acyltransferase; calcium-independent phospholipase A2-epsilon

Patatin-like phospholipase domain-containing protein 3

Adpn; iPLA2-epsilon??[Similar Products]

PLPL3_MOUSE

PNPLA3: Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities. Genetic variations in PNPLA3 are a cause of susceptibility to non-alcoholic fatty liver disease type 1 (NAFLD1). A condition characterized by an accumulation of excess triglyceride in the liver, a condition known as hepatic steatosis (or fatty liver), which is associated with adverse metabolic consequences, including insulin resistance and dyslipidemia. In a subset of individuals, hepatic steatosis promotes an inflammatory response in the liver, referred to as steatohepatitis, which can progress to cirrhosis and liver cancer. NAFLD is the most common form of liver disease in Western countries. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - tyrosine; Lipid Metabolism - glycerophospholipid; Transferase; Amino Acid Metabolism - phenylalanine; Phospholipase; EC 3.1.1.3; Lipid Metabolism - glycerolipid; Secondary Metabolites Metabolism - limonene and pinene degradation; Membrane protein, integral

Cellular Component: membrane; integral to membrane

Molecular Function: phospholipase A2 activity; triacylglycerol lipase activity; keto acid formate lyase activity; glucosaminyl-phosphotidylinositol O-acyltransferase activity; S-malonyltransferase activity; 3-hydroxybutyryl-CoA thiolase activity; S-acetyltransferase activity; O-octanoyltransferase activity; O-sinapoyltransferase activity; acyl-CoA N-acyltransferase activity; peptidyl-lysine N6-myristoyltransferase activity; palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity; peptidyl-lysine N6-palmitoyltransferase activity; azetidine-2-carboxylic acid acetyltransferase activity; succinyltransferase activity; dihydrolipoamide branched chain acyltransferase activity; Ras palmitoyltransferase activity; palmitoyltransferase activity; C-acyltransferase activity; C-palmitoyltransferase activity; dihydrolipoamide S-acyltransferase activity; N-acetyltransferase activity; protein-cysteine S-acyltransferase activity; serine O-acyltransferase activity; malonyltransferase activity; O-succinyltransferase activity; octanoyltransferase activity; O-palmitoyltransferase activity; hydrolase activity; 3-ketopimelyl-CoA thiolase activity; carnitine O-acyltransferase activity; sterol O-acyltransferase activity; S-succinyltransferase activity; N-acyltransferase activity; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity; O-acyltransferase activity; N-palmitoyltransferase activity; acylglycerol O-acyltransferase activity; O-acetyltransferase activity; transferase activity; benzoyl acetate-CoA thiolase activity; sinapoyltransferase activity; mono-olein transacylation activity; S-acyltransferase activity; protein-cysteine S-myristoyltransferase activity; acetyltransferase activity; myristoyltransferase activity; N-succinyltransferase activity; transferase activity, transferring acyl groups; L-2-aminoadipate N-acetyltransferase activity; diolein transacylation activity

Biological Process: metabolic process; triacylglycerol catabolic process; triacylglycerol biosynthetic process; lipid metabolic process; lipid catabolic process

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