Aldh3a2; aldehyde dehydrogenase 3 family, member A2; Aldh4; FALDH; alcohol dehydrogenase family 3, subfamily A2; aldehyde dehydrogenase 3A2; aldehyde dehydrogenase 4; aldehyde dehydrogenase family 3 member A2; aldehyde dehydrogenase family 3, subfamily A2

For Research Use Only. Not for use in diagnostic procedures.

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

Manufactured in an ISO 9001:2008 Certified Laboratory.

Small volumes of ALDH3A2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

54,082 Da

aldehyde dehydrogenase 3 family, member A2

fatty aldehyde dehydrogenase

Fatty aldehyde dehydrogenase

Aldh4; msALDH??[Similar Products]

AL3A2_RAT

ALDH3A2: Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. Defects in ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS). SLS is an autosomal recessive neurocutaneous disorder characterized by a combination of severe mental retardation, spastic di- or tetraplegia and congenital ichthyosis (increased keratinization). Ichthyosis is usually evident at birth, neurologic symptoms appear in the first or second year of life. Most patients have an IQ of less than 60. Additional clinical features include glistening white spots on the retina, seizures, short stature and speech defects. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Membrane protein, integral; Oxidoreductase; Mitochondrial; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - propanoate; Amino Acid Metabolism - histidine; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Other Amino Acids Metabolism - beta-alanine; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - arginine and proline; Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - ascorbate and aldarate; Amino Acid Metabolism - lysine degradation; Lipid Metabolism - glycerolipid; EC 1.2.1.3; Lipid Metabolism - fatty acid; Carbohydrate Metabolism - glycolysis and gluconeogenesis

Cellular Component: cytosol; endoplasmic reticulum; integral to membrane; intracellular membrane-bound organelle; mitochondrial inner membrane; mitochondrion; nucleus; peroxisome

Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; long-chain-alcohol oxidase activity; long-chain-aldehyde dehydrogenase activity

Biological Process: aldehyde metabolic process; central nervous system development; epidermis development; formaldehyde metabolic process; peripheral nervous system development; phytol metabolic process; response to reactive oxygen species; sesquiterpenoid metabolic process

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