Product Name
ALDH3A2, Polyclonal Antibody
Full Product Name
ALDH3A2 antibody - C-terminal region
Product Gene Name
anti-ALDH3A2 antibody
[Similar Products]
Product Synonym Gene Name
ALDH10; DKFZp686E23276; FALDH; SLS[Similar Products]
Antibody/Peptide Pairs
ALDH3A2 peptide (MBS3232256) is used for blocking the activity of ALDH3A2 antibody (MBS3207291)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: FINEREKPLA LYVFSHNHKL IKRMIDETSS GGVTGNDVIM HFTLNSFPFG
3D Structure
ModBase 3D Structure for Q60HH8
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 93%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ALDH3A2
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ALDH3A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ALDH3A2 antibody
This is a rabbit polyclonal antibody against ALDH3A2. It was validated on Western Blot and immunohistochemistry
Target Description: Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. ALDH3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid.Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome.
Product Categories/Family for anti-ALDH3A2 antibody
Polyclonal; Neuro
biology; Membrane Protein; Drugs and Drug Metabolism; Disease Related; Immunohistochemistry;
Applications Tested/Suitable for anti-ALDH3A2 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Immunohistochemistry (IHC) of anti-ALDH3A2 antibody
Human kidney
Western Blot (WB) of anti-ALDH3A2 antibody
WB Suggested Anti-ALDH3A2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
NCBI/Uniprot data below describe general gene information for ALDH3A2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000373
[Other Products]
NCBI GenBank Nucleotide #
NM_000382
[Other Products]
UniProt Primary Accession #
Q60HH8
[Other Products]
UniProt Related Accession #
P51648[Other Products]
NCBI Official Full Name
fatty aldehyde dehydrogenase isoform 2
NCBI Official Synonym Full Names
aldehyde dehydrogenase 3 family member A2
NCBI Official Symbol
ALDH3A2??[Similar Products]
NCBI Official Synonym Symbols
SLS; FALDH; ALDH10
??[Similar Products]
NCBI Protein Information
fatty aldehyde dehydrogenase
UniProt Protein Name
Fatty aldehyde dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase family 3 member A2
Protein Family
Fatty aldehyde dehydrogenase
UniProt Gene Name
ALDH3A2??[Similar Products]
NCBI Summary for ALDH3A2
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ALDH3A2
Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid ().
Research Articles on ALDH3A2
1. Homozygous ALDH3A2 mutations exhibited an unusual neuro-regressive clinical course associated with seizures in Sjogren-Larsson syndrome patients, which may reflect the presence of unidentified genetic or environmental modifiers in this consanguineous population.
Precautions
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Disclaimer
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