Product Name
PRG4, Blocking Peptide
Full Product Name
PRG4 Peptide - N-terminal region
Product Gene Name
PRG4 blocking peptide
[Similar Products]
Product Synonym Gene Name
MSF; SZP; CACP; HAPO; JCAP[Similar Products]
PRG4 peptide (MBS3245814) is used for blocking the activity of PRG4 antibody (MBS3221020)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: KIKSSKNSAA NRELQKKLKV KDNKKNRTKK KPTPKPPVVD EAGSGLDNGD
3D Structure
ModBase 3D Structure for J3KP74
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of PRG4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PRG4 blocking peptide
This is a synthetic peptide designed for use in combination with anti-PRG4 Antibody, made
Target Description: The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.
Product Categories/Family for PRG4 blocking peptide
Peptide
Applications Tested/Suitable for PRG4 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for PRG4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001121180.2
[Other Products]
NCBI GenBank Nucleotide #
NM_001127708.2
[Other Products]
UniProt Primary Accession #
J3KP74
[Other Products]
UniProt Related Accession #
Q92954[Other Products]
NCBI Official Full Name
proteoglycan 4 isoform B preproprotein
NCBI Official Synonym Full Names
proteoglycan 4
NCBI Official Symbol
PRG4??[Similar Products]
NCBI Official Synonym Symbols
MSF; SZP; CACP; HAPO; JCAP
??[Similar Products]
NCBI Protein Information
proteoglycan 4
Protein Family
Proteoglycan
NCBI Summary for PRG4
The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Research Articles on PRG4
1. Inflammatory Biomarker Profiling in Total Joint Arthroplasty and Its Relevance to Circulating Levels of Lubricin, a Novel Proteoglycan.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
