Product Name
Proteoglycan 4 (Prg4), ELISA Kit
Popular Item
Full Product Name
Mouse Proteoglycan 4 ELISA Kit
Product Synonym Names
Proteoglycan 4; Lubricin; Megakaryocyte-stimulating factor; Superficial zone proteoglycan; Prg4; Msf; Szp
Product Gene Name
Prg4 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q9JM99
Detection Range
1.56-100 ng/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Prg4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Prg4 purchase
MBS2880817 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Proteoglycan 4 (Prg4) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Prg4. The ELISA analytical biochemical technique of the MBS2880817 kit is based on Prg4 antibody-Prg4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Prg4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Prg4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for Prg4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001103616.1
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NCBI GenBank Nucleotide #
NM_001110146.1
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UniProt Primary Accession #
Q9JM99
[Other Products]
UniProt Secondary Accession #
Q3UEL1; Q3V198[Other Products]
UniProt Related Accession #
Q9JM99[Other Products]
Molecular Weight
47,989 Da
NCBI Official Full Name
proteoglycan 4 isoform 2
NCBI Official Synonym Full Names
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
NCBI Official Symbol
Prg4??[Similar Products]
NCBI Official Synonym Symbols
MSF; SZP; CACP; JCAP; DOL54; lubricin
??[Similar Products]
NCBI Protein Information
proteoglycan 4
UniProt Protein Name
Proteoglycan 4
UniProt Synonym Protein Names
Lubricin; Megakaryocyte-stimulating factor; Superficial zone proteoglycan
Protein Family
Proteoglycan
UniProt Gene Name
Prg4??[Similar Products]
UniProt Synonym Gene Names
Msf; Szp??[Similar Products]
UniProt Entry Name
PRG4_MOUSE
UniProt Comments for Prg4
PRG4: Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface. Defects in PRG4 are the cause of camptodactyly- arthropathy-coxa vara-pericarditis syndrome (CACP); also known as Jacobs syndrome. CACP is an autosomal recessive disorder. Individuals with CACP have normal appearing joints at birth but with advancing age develop joint failure associated with noninflammatory synoviocyte hyperplasia and subintimal fibrosis of the synovial capsule. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: extracellular region; extracellular space
Molecular Function: polysaccharide binding; scavenger receptor activity
Biological Process: immune response; negative regulation of interleukin-6 biosynthetic process; regulation of cell proliferation
Research Articles on Prg4
1. PRG4 is a novel putative ligand for CD44 and may control synoviocyte overgrowth in inflammatory arthropathies via a CD44-mediated mechanism.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
