Product Name
AMHR2, cDNA Clone
Full Product Name
AMHR2 cDNA Clone
Product Gene Name
AMHR2 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgctagggt ctttggggct ttgggcatta cttcccacag ctgtggaagc acccccaaac aggcgaacct gtgtgttctt tgaggcccct ggagtgcggg gaagcacaaa gacactggga gagctgctag atacaggcac agagctcccc agagctatcc gctgcctcta cagccgctgc tgctttggga tctggaacct gacccaagac cgggcacagg tggaaatgca aggatgccga gacagtgatg agccaggctg tgagtccctc cactgtgacc caagtccccg agcccacccc agccctggct ccactctctt cacctgctcc tgtggcactg acttctgcaa tgccaattac agccatctgc ctcctccagg gagccctggg actcctggct cccagggtcc ccaggctgcc ccaggtgagt ccatctggat ggcactggtg ctgctggggc tgttcctcct cctcctgctg ctgctgggca gcatcatctt ggccctgcta cagcgaaaga actacagagt gcgaggtgag ccagtgccag agccaaggcc agactcaggc agggactgga gtgtggagct gcaggagctg cctgagctgt gtttctccca ggtaatccgg gaaggaggtc atgcagtggt ttgggccggg cagctgcaag gaaaactggt tgccatcaag gccttcccac cgaggtctgt ggctcagttc caagctgaga gagcattgta cgaacttcca ggcctacagc acgaccacat tgtccgattt atcactgcca gccggggggg tcctggccgc ctgctctctg ggcccctgct ggtactggaa ctgcatccca agggctccct gtgccactac ttgacccagt acaccagtga ctggggaagt tccctgcgga tggcactgtc cctggcccag ggcctggcat ttctccatga ggagcgctgg cagaatggcc aatataaacc aggtattgcc caccgagatc tgagcagcca gaatgtgctc attcgggaag atggatcgtg tgccattgga gacctgggcc ttgccttggt gctccctggc ctcactcagc cccctgcctg gacccctact caaccacaag gcccagctgc catcatggaa gctggcaccc agaggtacat ggcaccagag ctcttggaca agactctgga cctacaggat tggggcatgg ccctccgacg agctgatatt tactctttgg ctctgctcct gtgggagata ctgagccgct gcccagattt gaggcctgac agcagtccac cacccttcca actggcctat gaggcagaac tgggcaatac ccctacctct gatgagctat gggccttggc agtgcaggag aggaggcgtc cctacatccc atccacctgg cgctgctttg ccacagaccc tgatgggctg agggagctcc tagaagactg ttgggatgca gacccagaag cacggctgac agctgagtgt gtacagcagc gcctggctgc cttggcccat cctcaagaga gccacccctt tccagagagc tgtccacgtg gctgcccacc tctctgccca gaagactgta cttcaattcc tgcccctacc atcctcccct gtaggcctca gcggagtgcc tgccacttca gcgttcagca aggcccttgt tccaggaatc ctcagcctgc ctgtaccctt tctcctgtgt aa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of AMHR2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AMHR2. It may not necessarily be applicable to this product.
NCBI Accession #
BC126316
[Other Products]
UniProt Secondary Accession #
Q13762; Q647K2; A0AVE1; B9EGB7; E9PGD2; F8W1D2[Other Products]
UniProt Related Accession #
Q16671[Other Products]
Molecular Weight
51,827 Da
NCBI Official Full Name
Homo sapiens anti-Mullerian hormone receptor, type II, mRNA
NCBI Official Synonym Full Names
anti-Mullerian hormone receptor type 2
NCBI Official Symbol
AMHR2??[Similar Products]
NCBI Official Synonym Symbols
AMHR; MRII; MISR2; MISRII
??[Similar Products]
NCBI Protein Information
anti-Muellerian hormone type-2 receptor
UniProt Protein Name
Anti-Muellerian hormone type-2 receptor
UniProt Synonym Protein Names
Anti-Muellerian hormone type II receptor; AMH type II receptor; MIS type II receptor; MISRII; MRII
Protein Family
Anti-Muellerian hormone type-2 receptor
UniProt Gene Name
AMHR2??[Similar Products]
UniProt Synonym Gene Names
AMHR; MISR2; AMH type II receptor; MISRII; MRII??[Similar Products]
UniProt Entry Name
AMHR2_HUMAN
NCBI Summary for AMHR2
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]
UniProt Comments for AMHR2
MISR2: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Protein type: EC 2.7.11.30; Protein kinase, Ser/Thr (receptor); Protein kinase, TKL; Kinase, protein; Membrane protein, integral; TKL group; STKR family; Type2 subfamily
Chromosomal Location of Human Ortholog: 12q13
Molecular Function: hormone binding; protein binding; receptor activity
Biological Process: sex differentiation; signal transduction
Disease: Persistent Mullerian Duct Syndrome, Types I And Ii
Research Articles on AMHR2
1. There is no association between single nucleotide polymorphisms in the AMH/AMHR2 signaling pathway and early ovarian hyperstimulation syndrome in Han Chinese women
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
