Product Name
Cytochrome b reductase 1 (Cybrd1), Polyclonal Antibody
Full Product Name
Anti-Cytochrome b reductase 1 Antibody
Product Gene Name
anti-Cybrd1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q5RKJ2
Purity/Purification
Affinity Purified
Concentration
100ug/200ul (lot specific)
Immunogen
CRNLALDEAGQRSTM
Storage Buffer
Supplied at 0.5 mg/ml in Tris saline,0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Other Notes
Small volumes of anti-Cybrd1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-Cybrd1 antibody
Western Blot (WB), ELISA (EIA)
NCBI/Uniprot data below describe general gene information for Cybrd1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001011954.1
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NCBI GenBank Nucleotide #
NM_001011954.1
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UniProt Primary Accession #
Q5RKJ2
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UniProt Related Accession #
Q5RKJ2[Other Products]
Molecular Weight
31,519 Da[Similar Products]
NCBI Official Full Name
cytochrome b reductase 1
NCBI Official Synonym Full Names
cytochrome b reductase 1
NCBI Official Symbol
Cybrd1??[Similar Products]
NCBI Official Synonym Symbols
Dcytb
??[Similar Products]
NCBI Protein Information
cytochrome b reductase 1
UniProt Protein Name
Cytochrome b reductase 1
UniProt Synonym Protein Names
Duodenal cytochrome b
Protein Family
Cytochrome b reductase
UniProt Gene Name
Cybrd1??[Similar Products]
UniProt Synonym Gene Names
Dcytb??[Similar Products]
UniProt Comments for Cybrd1
CYBRD1: Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.-.-.-; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Oxidoreductase; Transporter; Transporter, ion channel; Transporter, iron
Chromosomal Location of Human Ortholog: 3q22
Cellular Component: brush border membrane
Molecular Function: ferric-chelate reductase activity; oxidoreductase activity
Biological Process: response to iron ion
Research Articles on Cybrd1
1. Data suggest that expression of Cybrd1 in intestinal mucosa can be regulated by dietary factors; here, expression of Cybrd1 in mucosa of duodenum is up-regulated by prebiotic supplement, inulin, in iron-deficiency anemia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
