Full Product Name
ALG12 Antibody - N-terminal region
Product Gene Name
anti-ALG12 antibody
[Similar Products]
Product Synonym Gene Name
ALG12; PP14673;[Similar Products]
Antibody/Peptide Pairs
ALG12 peptide (MBS3234601) is used for blocking the activity of ALG12 antibody (MBS3209645)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: EESFNLQATH DLLYHWQDLE QYDHLEFPGV VPRTFLGPVV IAVFSSPAVY
3D Structure
ModBase 3D Structure for Q9BV10
Species Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 93%; Goat: 79%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 85%; Zebrafish: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human ALG12
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ALG12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ALG12 antibody
This is a rabbit polyclonal antibody against ALG12. It was validated on Western Blot
Target Description: This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation.
Product Categories/Family for anti-ALG12 antibody
Polyclonal; Disease Related;
Applications Tested/Suitable for anti-ALG12 antibody
Western Blot (WB)
Western Blot (WB) of anti-ALG12 antibody
Host: Rabbit
Target Name: ALG12
Sample Type: 293T Whole Cell lysates
Antibody Dilution: 1.0ug/ml
NCBI/Uniprot data below describe general gene information for ALG12. It may not necessarily be applicable to this product.
NCBI Accession #
NP_077010
[Other Products]
NCBI GenBank Nucleotide #
NM_024105.4
[Other Products]
UniProt Primary Accession #
Q9BV10
[Other Products]
UniProt Related Accession #
Q9BV10[Other Products]
NCBI Official Full Name
dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase
NCBI Official Synonym Full Names
ALG12 alpha-1,6-mannosyltransferase
NCBI Official Symbol
ALG12??[Similar Products]
NCBI Official Synonym Symbols
CDG1G; ECM39; hALG12; PP14673
??[Similar Products]
NCBI Protein Information
dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase
UniProt Protein Name
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase
UniProt Synonym Protein Names
Asparagine-linked glycosylation protein 12 homolog; hALG12; Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase; Mannosyltransferase ALG12 homolog; Membrane protein SB87
UniProt Gene Name
ALG12??[Similar Products]
UniProt Synonym Gene Names
PP14673; hALG12??[Similar Products]
UniProt Entry Name
ALG12_HUMAN
NCBI Summary for ALG12
This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq, Jul 2008]
Research Articles on ALG12
1. deficiency results in congenital disorders of glycosylation type Ig
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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