Product Name
CFHR3, Polyclonal Antibody
Popular Item
Full Product Name
CFHR3 Polyclonal Antibody
Product Synonym Names
CFHL3; DOWN16; FHR-3; FHR3; HLF4
Product Gene Name
anti-CFHR3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
AVPCLRKCYF PYLENGYNQN YGRKFVQGNS TEVACHPGYG LPKAQTTVTC TEKGWSPTPR CIRVRTCSKS DIEIENGFIS ESSSIYILNK EIQYKCKPGY ATADGNSSGS ITCLQNGWSA Q
3D Structure
ModBase 3D Structure for Q02985
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human CFHR3
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Secreted
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-CFHR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CFHR3 antibody
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-CFHR3 antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-CFHR3 antibody
Immunofluorescence (IF)
Application Notes for anti-CFHR3 antibody
IF: 1:50 - 1:200
Immunofluorescence (IF) of anti-CFHR3 antibody
Immunofluorescence analysis of A549 cells using CFHR3 antibody. Blue: DAPI for nuclear staining.
NCBI/Uniprot data below describe general gene information for CFHR3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001160096.1
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NCBI GenBank Nucleotide #
NM_001166624.1
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UniProt Primary Accession #
Q02985
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UniProt Secondary Accession #
Q9UJ16; B4DPR0[Other Products]
UniProt Related Accession #
Q02985[Other Products]
Molecular Weight
30kDa/37kDa
NCBI Official Full Name
complement factor H-related protein 3 isoform 2
NCBI Official Synonym Full Names
complement factor H related 3
NCBI Official Symbol
CFHR3??[Similar Products]
NCBI Official Synonym Symbols
FHR3; HLF4; CFHL3; FHR-3; DOWN16
??[Similar Products]
NCBI Protein Information
complement factor H-related protein 3
UniProt Protein Name
Complement factor H-related protein 3
UniProt Synonym Protein Names
DOWN16; H factor-like protein 3
Protein Family
Complement factor H-related protein
UniProt Gene Name
CFHR3??[Similar Products]
UniProt Synonym Gene Names
CFHL3; FHR3; FHR-3??[Similar Products]
NCBI Summary for CFHR3
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for CFHR3
Might be involved in complement regulation.
Research Articles on CFHR3
1. To our knowledge, this is the first evaluation of the involvement of the CFHR3/CFHR1 deletion and age-related macular degeneration in CFH Y402H polymorphism Brazilian patients.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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