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Cadherin 16, Polyclonal Antibody

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產(chǎn)品名稱: Cadherin 16, Polyclonal Antibody
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Cadherin 16, Polyclonal Antibody


Cadherin 16, Polyclonal Antibody  的詳細(xì)介紹
Product Name

Cadherin 16 (CDH16), Polyclonal Antibody

Full Product Name

Polyclonal Antibody to Cadherin 16 (CDH16)

Product Gene Name

anti-CDH16 antibody

[Similar Products]
Matching Pairs
Unconjugated Antibody: Cadherin 16 (MBS2026681)
Immunogen: Cadherin 16 (MBS2031338)
Matching Pairs
Unconjugated Antibody: Cadherin 16 (MBS2026681)
APC-CY7 Conjugated Antibody: Cadherin 16 (CDH16) (MBS2061849)
Matching Pairs
Unconjugated Antibody: Cadherin 16 (MBS2026681)
PE Conjugated Antibody: Cadherin 16 (CDH16) (MBS2061850)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- PGTEIARL SAEDLDAPGS PNSHIVYQLL SPEPEEGAEN KAFELDPTSG SVTLGTAPLH AGQSILLQVL AVDLAGSESG LSSTCEVTVM VTDVNNHAPE FINSQIGPVT LPEDVKPGAL VATLMATDAD LEPAFRLMDF AIEEGDPEGI FDLSWEPDSD HVQLRLRKNL SYEAAPDHKV VVVVSNIEEL VGPGPGPAAT ATVTILVERV VAPLKLDQES YETSIPVSTP AGSLLLTIQP SDPMSRTLRF SLVNDSEGWL
3D Structure
ModBase 3D Structure for O88338
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Specificity
The antibody is a rabbit polyclonal antibody raised against CDH16. It has beenselected for its ability to recognize CDH16 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
200ug/ml (lot specific)
Fragment
CDH16 (Pro353~Gly617)
Organism Species
Mus musculus (Mouse)
Conjugate
No Conjugate
Immunogen
Recombinant CDH16 (Pro353~Gly617) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2061851
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of anti-CDH16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-CDH16 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-CDH16 antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-CDH16 antibody
Western Blot: Sample: Recombinant CDH16, Mouse.
anti-CDH16 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CDH16 antibody
DAB staining on IHC-P; Samples: Mouse Heart Tissue
anti-CDH16 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CDH16 antibody
DAB staining on IHC-P; Samples: Mouse Intestine Tissue.
anti-CDH16 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CDH16 antibody
DAB staining on IHC-P; Samples: Mouse Kidney Tissue.
anti-CDH16 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CDH16 antibody
DAB staining on IHC-P; Samples: Mouse Brain Tissue.
anti-CDH16 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CDH16. It may not necessarily be applicable to this product.
NCBI GI #
6680900
NCBI GeneID
12556
NCBI Accession #
NP_031689.1 [Other Products]
NCBI GenBank Nucleotide #
NM_007663.3 [Other Products]
UniProt Primary Accession #
O88338 [Other Products]
UniProt Secondary Accession #
Q9JLZ5[Other Products]
UniProt Related Accession #
O88338[Other Products]
Molecular Weight
89,860 Da
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NCBI Official Full Name
cadherin-16 isoform 1
NCBI Official Synonym Full Names
cadherin 16
NCBI Official Symbol
Cdh16??[Similar Products]
NCBI Protein Information
cadherin-16
UniProt Protein Name
Cadherin-16
UniProt Synonym Protein Names
Kidney-specific cadherin; Ksp-cadherin
Protein Family
Cadherin
UniProt Gene Name
Cdh16??[Similar Products]
UniProt Synonym Gene Names
Ksp-cadherin??[Similar Products]
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UniProt Comments for CDH16
CDH16: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 8 D3|8 53.04 cM

Cellular Component: basolateral plasma membrane; integral component of membrane; integral component of plasma membrane; membrane; plasma membrane

Molecular Function: calcium ion binding; metal ion binding

Biological Process: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell adhesion; cell-cell signaling; homophilic cell adhesion; nervous system development
Research Articles on CDH16
1. study concludes that Cadherin-16 is a novel downstream target of the transcription factor Pax8, likely since the early steps of thyroid development, and that its expression is associated with the fully differentiated state of the thyroid cell
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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