Human Succinate dehydrogenase assembly factor 2; mitochondrial (C11orf79) ELISA kit; C11orf79; FLJ20487; PGL2; SDH5; paraganglioma or familial glomus tumors 2; chromosome 11 open reading frame 79

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of C11orf79 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9338279 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the chromosome 11 open reading frame 79 (C11orf79) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing C11orf79. The ELISA analytical biochemical technique of the MBS9338279 kit is based on C11orf79 antibody-C11orf79 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect C11orf79 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, C11orf79. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

19,599 Da

succinate dehydrogenase complex assembly factor 2

succinate dehydrogenase assembly factor 2, mitochondrial; hSDH5; SDH assembly factor 2; succinate dehydrogenase subunit 5, mitochondrial

Succinate dehydrogenase assembly factor 2, mitochondrial

C11orf79; PGL2; SDH5; SDH assembly factor 2; hSDH5??[Similar Products]

SDHF2_HUMAN

This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.[provided by RefSeq, Jul 2010]

SDH5: a subunit of succinate dehydrogenase (SDH) complex II of the mitochondrial electron transport chain. SDH5 is required for insertion of FAD cofactor into SDHA, the catalytic subunit of succinate dehydrogenase (SDH) complex II. SDH is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Mutated in some cancers. Germline mutations cause hereditary paragangliomas type 2, or non-chromaffin paragangliomas type 2. Paragangliomas are rare tumors that arise from components of the neuroendocrine system.

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: protein binding

Biological Process: mitochondrial electron transport, succinate to ubiquinone; protein-FAD linkage; protein amino acid dephosphorylation

Disease: Paragangliomas 2

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