Product Synonym Names
CFHL3; DOWN16; FHR-3; FHR3; HLF4
Product Gene Name
anti-CFHR3 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q02985
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purification
Immunogen
Recombinant protein of human CFHR3
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-CFHR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CFHR3 antibody
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Applications Tested/Suitable for anti-CFHR3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-CFHR3 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:100
NCBI/Uniprot data below describe general gene information for CFHR3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001160096.1
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NCBI GenBank Nucleotide #
NM_001166624.1
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UniProt Primary Accession #
Q02985
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UniProt Secondary Accession #
Q9UJ16; B4DPR0[Other Products]
UniProt Related Accession #
Q02985[Other Products]
NCBI Official Full Name
complement factor H-related protein 3 isoform 2
NCBI Official Synonym Full Names
complement factor H related 3
NCBI Official Symbol
CFHR3??[Similar Products]
NCBI Official Synonym Symbols
FHR3; HLF4; CFHL3; FHR-3; DOWN16
??[Similar Products]
NCBI Protein Information
complement factor H-related protein 3
UniProt Protein Name
Complement factor H-related protein 3
UniProt Synonym Protein Names
DOWN16; H factor-like protein 3
Protein Family
Complement factor H-related protein
UniProt Gene Name
CFHR3??[Similar Products]
UniProt Synonym Gene Names
CFHL3; FHR3; FHR-3??[Similar Products]
NCBI Summary for CFHR3
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for CFHR3
Might be involved in complement regulation.
Research Articles on CFHR3
1. We conclude that the relationship between complement-regulatory proteins CFHR1 and CFHR3 and response to anti-CD20 mAb therapy varies based on the specific anti-CD20 mAb used.
Precautions
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Disclaimer
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