Product Name
BOLL, cDNA Clone
Full Product Name
BOLL cDNA Clone
Product Gene Name
BOLL cdna clone
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgcaaacag attcattatc tccatcccct aatcctgtgt cacctgtgcc tttgaataac ccaacaagtg ccccaagata tggaacagtg atccctaatc gcatctttgt aggaggaatt gattttaaga caaacgaaag tgatttaaga aaattttttt cccagtatgg gtctgtgaaa gaagtgaaga ttgtaaatga cagagctgga gtatccaaag ggtatggttt cgtcactttt gaaacacaag aagatgcaca aaaaatttta caagaggctg aaaaacttaa ttataaggat aagaagctga acattggtcc agcaataaga aaacaacaag tagggatccc tcgttctagt ataatgccag cagctggaac aatgtatcta acaacttcaa ctggatatcc ttatacttac cataatggtg ttgcttattt tcatactcca gaggtaactt cggtcccacc gccttggcct tcacgttctg tatgtagctc ccctgtgatg gtagctcagc ccatttatca gcaacctgca tatcactacc aggccaccac acagtattta ccaggacagt ggcagtggag tgttcctcag ccttctgcct cttctgctcc attcttatac ctgcaacctt ctgaggttat ttatcaacca gtggaaattg cacaggatgg tggatgtgtt cctcctccac tgtctctgat ggaaacttca gttccagagc cttattctga tcatggagtt caagcaacat atcaccaggt ttatgctcca agtgccatca ctatgcctgc gcctgtgatg cagcctgagc caattaaaac agtgtggagc attcattatt aa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of BOLL cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for BOLL. It may not necessarily be applicable to this product.
NCBI Accession #
BC033674
[Other Products]
UniProt Secondary Accession #
Q0JW32; Q53T62; Q969U3; B4DZA4[Other Products]
UniProt Related Accession #
Q8N9W6[Other Products]
Molecular Weight
19,256 Da
NCBI Official Full Name
Homo sapiens bol, boule-like (Drosophila), mRNA
NCBI Official Synonym Full Names
boule homolog, RNA binding protein
NCBI Official Symbol
BOLL??[Similar Products]
NCBI Official Synonym Symbols
BOULE
??[Similar Products]
NCBI Protein Information
protein boule-like
UniProt Protein Name
Protein boule-like
Protein Family
Protein boule
UniProt Gene Name
BOLL??[Similar Products]
UniProt Synonym Gene Names
BOULE??[Similar Products]
UniProt Entry Name
BOLL_HUMAN
NCBI Summary for BOLL
This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for BOLL
BOLL: Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Belongs to the RRM DAZ family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation
Chromosomal Location of Human Ortholog: 2q33
Cellular Component: cytoplasm
Molecular Function: protein binding; translation activator activity
Biological Process: meiosis; positive regulation of translational initiation
Research Articles on BOLL
1. Our study demonstrated an oncogenic role of BOLL in CRC despite tumor-specific promoter hypermethylation.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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