Full Product Name
BOLL, NT (BOLL, BOULE, Protein boule-like)
Product Synonym Names
Anti -BOLL, NT (BOLL, BOULE, Protein boule-like)
Product Gene Name
anti-BOLL antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8N9W6
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Immunogen
BOLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human BOLL.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-BOLL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BOLL antibody
BOLL belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition.
Product Categories/Family for anti-BOLL antibody
Antibodies; Abs to Spermatogenesis, Testis Proteins
Applications Tested/Suitable for anti-BOLL antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-BOLL antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
NCBI/Uniprot data below describe general gene information for BOLL. It may not necessarily be applicable to this product.
NCBI Accession #
CAL25726.1
[Other Products]
UniProt Primary Accession #
Q8N9W6
[Other Products]
UniProt Secondary Accession #
Q0JW32; Q53T62; Q969U3[Other Products]
Molecular Weight
31,301 Da[Similar Products]
NCBI Official Full Name
boll protein
UniProt Protein Name
Protein boule-like
Protein Family
Protein boule
UniProt Gene Name
BOLL??[Similar Products]
UniProt Synonym Gene Names
BOULE??[Similar Products]
UniProt Entry Name
BOLL_HUMAN
UniProt Comments for BOLL
BOLL: Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Belongs to the RRM DAZ family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation
Chromosomal Location of Human Ortholog: 2q33
Cellular Component: cytoplasm
Molecular Function: protein binding; translation activator activity; RNA binding; nucleotide binding
Biological Process: positive regulation of translational initiation; meiosis; multicellular organismal development; spermatogenesis; cell differentiation
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
