BPIFA1; BPI fold containing family A, member 1; LPLUNC3; LUNX; NASG; PLUNC; SPLUNC1; SPURT; bA49G10.5; OTTHUMP00000030625; OTTHUMP00000030626; OTTHUMP00000030627; ligand-binding protein RYA3; lung-specific protein X; nasopharyngeal carcinoma-related prote; bA49G10.5 antibody; BPI fold containing family A; member 1 antibody; BPIFA1 antibody; ligand-binding protein RYA3 antibody; LPLUNC3 antibody; lung-specific protein X antibody; LUNX antibody; NASG antibody; nasopharyngeal carcinoma-related protein antibody; OTTHUMP00000030625 antibody; OTTHUMP00000030626 antibody; OTTHUMP00000030627 antibody; palate lung and nasal epithelium clone protein antibody; palate; lung and nasal epithelium associated antibody; PLUNC antibody; protein Plunc antibody; secretory protein in upper respiratory tracts antibody; SPLUNC1 antibody; SPURT antibody; tracheal epithelium enriched protein antibody; tracheal epithelium-enriched protein antibody; von Ebner protein Hl antibody; BPIFA1 / PLUNC

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Goat

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul (lot specific)

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Manufactured in an ISO 9001:2008 Certified Laboratory.

Small volumes of anti-BPIFA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Peptide ELISA (EIA), Western Blot (WB)

Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx 26kDa band observed in secretions of Human primary airway cells in culture-and in Human Bronchoalveolar Lavage fluid (calculated MW of 26.7kDa according to NP_057667.1). Recommended concentration: 1-3ug/ml.

(2ug/ml) staining of secretions from Human primary airway cells in culture (lanes 1 and 2), and in Human Bronchoalveolar Lavage fluid (lanes 3 and 4). Data obtained from Dr. C Bingle, AURM, University of Sheffield, UK. Primary incubation was 1 hour. Detected by chemiluminescence.

25,257 Da

BPI fold containing family A member 1

BPI fold-containing family A member 1

BPI fold-containing family A member 1

LUNX; NASG; PLUNC; SPLUNC1; SPURT; SPLUNC1??[Similar Products]

BPIA1_HUMAN

This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014]

PLUNC: May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways. Belongs to the BPI/LBP/Plunc superfamily. Plunc family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20q11.2

Cellular Component: extracellular region; extracellular space

Molecular Function: lipid binding; protein binding

Biological Process: antibacterial humoral response; innate immune response; multicellular organismal water homeostasis; regulation of liquid surface tension

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