Product Name
Interleukin 31 (IL31), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Interleukin 31 (IL31)
Product Gene Name
anti-IL31 antibody
[Similar Products]
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
Immunogen: Interleukin 31 (MBS2030488)
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
APC-CY7 Conjugated Antibody: Interleukin 31 (IL31) (MBS2052171)
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
PE Conjugated Antibody: Interleukin 31 (IL31) (MBS2052172)
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
APC Conjugated Antibody: Interleukin 31 (IL31) (MBS2052173)
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
Cy3 Conjugated Antibody: Interleukin 31 (IL31) (MBS2052174)
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
FITC Conjugated Antibody: Interleukin 31 (IL31) (MBS2052175)
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
HRP Conjugated Antibody: Interleukin 31 (IL31) (MBS2052176)
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
Matching Pairs
Unconjugated Antibody: Interleukin 31 (MBS2028590)
Biotin Conjugated Antibody: Interleukin 31 (IL31) (MBS2092950)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6EAL8
Specificity
The antibody is a rabbit polyclonal antibody raised against IL31. It has beenselected for its ability to recognize IL31 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Concentration
200ug/ml (lot specific)
Fragment
IL31 (Ser28~Glu154)
Organism Species
Mus musculus (Mouse)
Immunogen
Recombinant IL31 (Ser28~Glu154) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2052173
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of anti-IL31 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-IL31 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-IL31 antibody
Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
Western Blot (WB) of anti-IL31 antibody
Western Blot: Sample: Recombinant IL31, Mouse.

Immunohistochemistry (IHC) of anti-IL31 antibody
DAB staining on fromalin fixed paraffin-embedded Liver tissue)

NCBI/Uniprot data below describe general gene information for IL31. It may not necessarily be applicable to this product.
NCBI Accession #
NP_083870.1
[Other Products]
NCBI GenBank Nucleotide #
NM_029594.1
[Other Products]
UniProt Primary Accession #
Q6EAL8
[Other Products]
UniProt Related Accession #
Q6EAL8[Other Products]
Molecular Weight
18,120 Da
NCBI Official Full Name
interleukin-31
NCBI Official Synonym Full Names
interleukin 31
NCBI Official Symbol
Il31??[Similar Products]
NCBI Official Synonym Symbols
1700013B14Rik
??[Similar Products]
NCBI Protein Information
interleukin-31
UniProt Protein Name
Interleukin-31
Protein Family
Interleukin
UniProt Gene Name
Il31??[Similar Products]
UniProt Synonym Gene Names
IL-31??[Similar Products]
UniProt Comments for IL31
IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity
Protein type: Cytokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 5|5 F
Cellular Component: extracellular region; extracellular space
Molecular Function: cytokine activity; cytokine receptor binding; oncostatin-M receptor binding; protein binding
Biological Process: immune system process
Research Articles on IL31
1. IL31 and its receptor, IL31RA, are highly expressed in various human and mouse cancer cell lines, as well as in tumor specimens from cancer patients. MC38 murine colon carcinoma cells depleted of IL31 exhibit an increase in invasive and migratory properties in vitro.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.