Full Product Name
Clcn1 antibody - C-terminal region
Product Gene Name
anti-CLCN1 antibody
[Similar Products]
Product Synonym Gene Name
SMCC; Clcn1[Similar Products]
Antibody/Peptide Pairs
Clcn1 peptide (MBS3227334) is used for blocking the activity of Clcn1 antibody (MBS3202356)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: SSIFQRLLHC LLGKAHSTKK KITQDSTDLV DNMSPEEIEA WEREQLSQPV
3D Structure
ModBase 3D Structure for P35524
Species Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 93%; Dog: 86%; Goat: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide corresponding to a region of Rat
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-CLCN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CLCN1 antibody
This is a rabbit polyclonal antibody against Clcn1. It was validated on Western Blot
Target Description: Clcn1 is the voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.
Product Categories/Family for anti-CLCN1 antibody
Polyclonal; Ion Channel;
Applications Tested/Suitable for anti-CLCN1 antibody
Western Blot (WB)
Western Blot (WB) of anti-CLCN1 antibody
Lanes:
1: 20ug mouse muscle membrane fraction, 2: Empty, 3: 20ug mouse brain membrane fraction, 4: Empty, 5: 20ug mouse muscle cytosolic fraction, 6: 20ug mouse brain cytosolic fraction
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit HRP
Secondary Antibody Dilution:
1:2000
Gene Name:
Clcn1
Submitted by:
Anonymous
Western Blot (WB) of anti-CLCN1 antibody
WB Suggested Anti-Clcn1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Rat Brain
NCBI/Uniprot data below describe general gene information for CLCN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_037279
[Other Products]
NCBI GenBank Nucleotide #
NM_013147
[Other Products]
UniProt Primary Accession #
P35524
[Other Products]
UniProt Related Accession #
P35524[Other Products]
NCBI Official Full Name
chloride channel protein 1
NCBI Official Synonym Full Names
chloride voltage-gated channel 1
NCBI Official Symbol
Clcn1??[Similar Products]
NCBI Official Synonym Symbols
SMCC
??[Similar Products]
NCBI Protein Information
chloride channel protein 1
UniProt Protein Name
Chloride channel protein 1
UniProt Synonym Protein Names
Chloride channel protein, skeletal muscle
Protein Family
Chloride channel protein
UniProt Gene Name
Clcn1??[Similar Products]
UniProt Synonym Gene Names
ClC-1??[Similar Products]
UniProt Entry Name
CLCN1_RAT
NCBI Summary for CLCN1
plays a role in chloride ion transport and membrane conductance in skeletal muscle [RGD, Feb 2006]
Research Articles on CLCN1
1. Regulation of ClC-1 in action potential-firing fast-twitch muscle fibers
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
