Human Dermatan-sulfate epimerase (DSE) ELISA kit; DSEPI; SART2; OTTHUMP00000017059; squamous cell carcinoma antigen recognized by T cells 2; dermatan sulfate epimerase

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of DSE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9317868 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the dermatan sulfate epimerase (DSE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DSE. The ELISA analytical biochemical technique of the MBS9317868 kit is based on DSE antibody-DSE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DSE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DSE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

109,773 Da

dermatan sulfate epimerase

dermatan-sulfate epimerase; DS epimerase; chondroitin-glucuronate 5-epimerase; squamous cell carcinoma antigen recognized by T-cells 2

Dermatan-sulfate epimerase

SART2; DS epimerase; SART-2??[Similar Products]

DSE_HUMAN

The protein encoded by this gene is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

SART2: Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. Belongs to the dermatan-sulfate isomerase family.

Protein type: Glycan Metabolism - chondroitin sulfate biosynthesis; Membrane protein, integral; EC 5.1.3.19; Membrane protein, multi-pass; Endoplasmic reticulum; Isomerase

Chromosomal Location of Human Ortholog: 6q22

Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum; integral to membrane

Molecular Function: chondroitin-glucuronate 5-epimerase activity

Biological Process: chondroitin sulfate metabolic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; heparan sulfate proteoglycan biosynthetic process; pathogenesis; dermatan sulfate biosynthetic process

Disease: Ehlers-danlos Syndrome, Musculocontractural Type 2

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