Full Product Name
ALX4 antibody - middle region
Product Gene Name
anti-ALX4 antibody
[Similar Products]
Product Synonym Gene Name
FPP; KIAA1788; PFM; PFM1; P***; FND2[Similar Products]
Antibody/Peptide Pairs
ALX4 peptide (MBS3226424) is used for blocking the activity of ALX4 antibody (MBS3201402)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: GQTHMGSLFG AASLSPGLNG YELNGEPDRK TSSIAALRMK AKEHSAAISW
3D Structure
ModBase 3D Structure for Q9H161
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ALX4
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ALX4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ALX4 antibody
This is a rabbit polyclonal antibody against ALX4. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: ALX4 is a member of the ALX homeobox gene family in humans. The paired-type homeodomain has been shown to mediate high-affinity sequence-specific DNA binding to palindromic elements as either homodimers or as heterodimers with other family members.
Product Categories/Family for anti-ALX4 antibody
Polyclonal; Transcription Factor; Transcription Regulation; Transcription Regulation; DNA/RNA/Protein Interactions; Transcription Factors;
Applications Tested/Suitable for anti-ALX4 antibody
Western Blot (WB)
Western Blot (WB) of anti-ALX4 antibody
WB Suggested Anti-ALX4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human Muscle

NCBI/Uniprot data below describe general gene information for ALX4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_068745
[Other Products]
NCBI GenBank Nucleotide #
NM_021926
[Other Products]
UniProt Primary Accession #
Q9H161
[Other Products]
UniProt Related Accession #
Q9H161[Other Products]
NCBI Official Full Name
homeobox protein aristaless-like 4
NCBI Official Synonym Full Names
ALX homeobox 4
NCBI Official Symbol
ALX4??[Similar Products]
NCBI Official Synonym Symbols
CRS5; FND2
??[Similar Products]
NCBI Protein Information
homeobox protein aristaless-like 4
UniProt Protein Name
Homeobox protein aristaless-like 4
Protein Family
Homeobox protein
UniProt Gene Name
ALX4??[Similar Products]
UniProt Synonym Gene Names
KIAA1788??[Similar Products]
UniProt Entry Name
ALX4_HUMAN
NCBI Summary for ALX4
This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (P***); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, cognitive disability, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009]
Research Articles on ALX4
1. We reveal for the first time that ALX4 acts as a novel functional tumor suppressor inactivated by DNA methylation and is an independent prognostic factor in breast cancer
Precautions
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Disclaimer
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