Product Name
SLC2A2, cDNA Clone
Popular Item
Full Product Name
SLC2A2 cDNA Clone
Product Gene Name
SLC2A2 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtatatcg gtgaaattgc tccaaccgct ctcaggggag cacttggcac ttttcatcag ctggccatcg tcacgggcat tcttattagt cagattattg gtcttgaatt tatcttgggc aattatgatc tgtggcacat cctgcttggc ctgtctggtg tgcgagccat ccttcagtct ctgctactct ttttctgtcc agaaagcccc agataccttt acatcaagtt agatgaggaa gtcaaagcaa aacaaagctt gaaaagactc agaggatatg atgatgtcac caaagatatt aatgaaatga gaaaagaaag agaagaagca tcgagtgagc agaaagtctc tataattcag ctcttcacca attccagcta ccgacagcct attctagtgg cactgatgct gcatgtggct cagcaatttt ccggaatcaa tggcattttt tactactcaa ccagcatttt tcagacggct ggtatcagca aacctgttta tgcaaccatt ggagttggcg ctgtaaacat ggttttcact gctgtctctg tattccttgt ggagaaggca gggcgacgtt ctctctttct aattggaatg agtgggatgt ttgtttgtgc catcttcatg tcagtgggac ttgtgctgct gaataagttc tcttggatga gttatgtgag catgatagcc atcttcctct ttgtcagctt ctttgaaatt gggccaggcc cgatcccctg gttcatggtg gctgagtttt tcagtcaagg accacgtcct gctgctttag caatagctgc attcagcaat tggacctgca atttcattgt agctctgtgt ttccagtaca ttgcggactt ctgtggacct tatgtgtttt tcctctttgc tggagtgctc ctggccttta ccctgttcac attttttaaa gttccagaaa ccaaaggaaa gtcttttgag gaaattgctg cagaattcca aaagaagagt ggctcagccc acaggccaaa agctgctgta gaaatgaaat tcctaggagc tacagagact gtgtaa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SLC2A2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SLC2A2. It may not necessarily be applicable to this product.
NCBI Accession #
BC060041
[Other Products]
UniProt Secondary Accession #
Q9UCW9; A8K481; B2R936; B7Z547; F8W8V8[Other Products]
UniProt Related Accession #
P11168[Other Products]
Molecular Weight
44,702 Da
NCBI Official Full Name
Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 2, mRNA
NCBI Official Synonym Full Names
solute carrier family 2 member 2
NCBI Official Symbol
SLC2A2??[Similar Products]
NCBI Official Synonym Symbols
GLUT2
??[Similar Products]
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 2
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 2
UniProt Synonym Protein Names
Glucose transporter type 2, liver; GLUT-2
Protein Family
Solute carrier family
UniProt Gene Name
SLC2A2??[Similar Products]
UniProt Synonym Gene Names
GLUT2; GLUT-2??[Similar Products]
UniProt Entry Name
GTR2_HUMAN
NCBI Summary for SLC2A2
This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
UniProt Comments for SLC2A2
GLUT2: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Present at high levels in the plasma membrane of pancreatic b-cells where it initiates the first step in glucose-stimulated insulin secretion, a glucose metabolism-dependent signaling mechanism. May mediate the bidirectional transfer of glucose across the plasma membrane of hepatocytes. May also participate with the Na( +2)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Required for glucose sensitivity in the hypothalamus and brain stem. Involved in the control of food intake and stimulation of glucose uptake by peripheral tissues.
Protein type: Transporter, SLC family; Membrane protein, integral; Transporter; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 3q26.1-q26.2
Cellular Component: integral to plasma membrane; membrane; plasma membrane
Molecular Function: D-glucose transmembrane transporter activity; glucose transmembrane transporter activity; hexose transmembrane transporter activity
Biological Process: carbohydrate metabolic process; glucose transport; hexose transport; regulation of insulin secretion
Disease: Diabetes Mellitus, Noninsulin-dependent; Fanconi-bickel Syndrome
Research Articles on SLC2A2
1. Three novel variants and seven single-nucleotide polymorphisms associated with the myelomeningocele phenotype.
Precautions
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Disclaimer
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