Product Name
DNAJC19, Polyclonal Antibody
Popular Item
Full Product Name
DNAJC19 Polyclonal Antibody
Product Synonym Names
PAM18; TIM14; TIMM14
Product Gene Name
anti-DNAJC19 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
MASTVVAVGL TIAAAGFAGR YVLQAMKHME PQVKQVFQSL PKSAFSGGYY RGGFEPKMTK REAALILGVS PTANKGKIRD AHRRIMLLNH PDKGGSPYIA AKINEAKDLL EGQAKK
3D Structure
ModBase 3D Structure for Q96DA6
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human DNAJC19
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Mitochondrion inner membrane, Single-pass membrane protein
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-DNAJC19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DNAJC19 antibody
The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19.
Product Categories/Family for anti-DNAJC19 antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-DNAJC19 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-DNAJC19 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
NCBI/Uniprot data below describe general gene information for DNAJC19. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001177162.1
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NCBI GenBank Nucleotide #
NM_001190233.1
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UniProt Primary Accession #
Q96DA6
[Other Products]
UniProt Secondary Accession #
B2R4B1; C9JBV1[Other Products]
UniProt Related Accession #
Q96DA6[Other Products]
Molecular Weight
10kDa/12kDa
NCBI Official Full Name
mitochondrial import inner membrane translocase subunit TIM14 isoform 2
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member C19
NCBI Official Symbol
DNAJC19??[Similar Products]
NCBI Official Synonym Symbols
PAM18; TIM14; TIMM14
??[Similar Products]
NCBI Protein Information
mitochondrial import inner membrane translocase subunit TIM14
UniProt Protein Name
Mitochondrial import inner membrane translocase subunit TIM14
UniProt Synonym Protein Names
DnaJ homolog subfamily C member 19
UniProt Gene Name
DNAJC19??[Similar Products]
UniProt Synonym Gene Names
TIM14; TIMM14??[Similar Products]
NCBI Summary for DNAJC19
The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19. [provided by RefSeq, Jan 2012]
UniProt Comments for DNAJC19
Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity ().
Research Articles on DNAJC19
1. Both DnaJC15 and DnaJC19 formed two distinct subcomplexes with Magmas at the import channel.
Precautions
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Disclaimer
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