Product Name
Bapx1 (NKX3-2), Polyclonal Antibody
Full Product Name
Bapx1 antibody - N-terminal region
Product Gene Name
anti-NKX3-2 antibody
[Similar Products]
Product Synonym Gene Name
NKX3.2; Nkx-3.2; Nkx3-2; Bapx1[Similar Products]
Antibody/Peptide Pairs
Bapx1 peptide (MBS3228290) is used for blocking the activity of Bapx1 antibody (MBS3203320)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: MAVRGSGTLT PFSIQAILNK KEERGGLATP EGRPAPGGTE VAVTAAPAVC
3D Structure
ModBase 3D Structure for P97503
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 83%; Human: 93%; Mouse: 100%; Rabbit: 100%; Rat: 83%; Zebrafish: 85%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of mouse Bapx1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-NKX3-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NKX3-2 antibody
This is a rabbit polyclonal antibody against Bapx1. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: Bapx1 acts as a negative regulator of chondrocyte maturation. The constitutive RelA activation mediated by Bapx1 controls chondrocyte viability.
Product Categories/Family for anti-NKX3-2 antibody
Polyclonal; Transcription Regulation; Transcription Factors;
Applications Tested/Suitable for anti-NKX3-2 antibody
Western Blot (WB)
Western Blot (WB) of anti-NKX3-2 antibody
Host: Rabbit
Target Name: Bapx1
Sample Type: Jurkat
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 0.5ug/mL
Peptide Concentration: 1.0ug/mL
Lysate Quantity: 25ug/lane
Gel Concentration: 12%

Western Blot (WB) of anti-NKX3-2 antibody
WB Suggested Anti-Bapx1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate

NCBI/Uniprot data below describe general gene information for NKX3-2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_031550
[Other Products]
NCBI GenBank Nucleotide #
NM_007524
[Other Products]
UniProt Primary Accession #
P97503
[Other Products]
UniProt Related Accession #
P97503[Other Products]
NCBI Official Full Name
homeobox protein Nkx-3.2
NCBI Official Synonym Full Names
NK3 homeobox 2
NCBI Official Symbol
Nkx3-2??[Similar Products]
NCBI Official Synonym Symbols
Bapx1; NKX3.2; Nkx-3.2
??[Similar Products]
NCBI Protein Information
homeobox protein Nkx-3.2
UniProt Protein Name
Homeobox protein Nkx-3.2
UniProt Synonym Protein Names
Bagpipe homeobox protein homolog 1; Homeobox protein NK-3 homolog B
Protein Family
Homeobox protein
UniProt Gene Name
Nkx3-2??[Similar Products]
UniProt Synonym Gene Names
Bapx1; Nkx-3.2; Nkx3b??[Similar Products]
UniProt Entry Name
NKX32_MOUSE
Research Articles on NKX3-2
1. these results suggest that Nkx3.2-mediated HIF regulation may allow cartilage-specific avascularity under hypoxic conditions during endochondral skeleton development.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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