cardiac muscle; Cardiac troponin I; cardiomyopathy; dilated 2A (autosomal recessive); Cardiomyopathy; familial hypertrophic; 7; included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; Tn1; Tni; TNN I3; TNNC 1; TNNC1; TNNI3; TNNI3_HUMAN; Troponin I; Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I; cardiac 3; TroponinI; Ttroponin I type 3 (cardiac)

For Research Use Only. Not for use in diagnostic procedures.

Monclonal

IgG2a

4D3-F3

Mouse

This antibody detects endogenous levels of Cardiac Troponin I.

Affinity Purified

PBS(pH 7.4) containing with 0.03% Proclin300.

Store at 4 degree C for short term.
Avoid freeze/thaw cycle.

Small volumes of anti-CTNI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Western Blot (WB), ELISA (EIA)

ELISA: 1:10000
WB: 1:1000

Western blot analysis of extracts from Rat and mouse heart tissue using Troponin I (MBS477384, dilution 1:1000) Mouse mAb.Predicted band size:28kDa.Observed band size:28kDa.

sELISA standard Curve for Cardiac Troponin I: Capture Antibody Mouse mAb to Cardiac Troponin I at 2ug/ml and MBS477384(4D3-F3) was used for detecting.

28kDa

troponin I3, cardiac type

troponin I, cardiac muscle

Troponin I, cardiac muscle

TNNC1??[Similar Products]

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

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