Anti -AVPR1B (AAvpr1b, Arginine Vasopressin Receptor 1B, AVPR3, Antidiuretic Hormone Receptor 1B, Arginine Vasopressin Receptor 3, Pituitary Vasopressin Receptor 3, Vasopressin V1B Receptor; AVPR3, V3/V1b, VIBR, VPR; V3/V1b pituitary vasopressin receptor, VPR3)

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 1; NC_000001.10 (206224283..206231482). Location: 1q32

Polyclonal

IgG

Goat

Recognizes rat AVPR1B. Sequence Homology: mouse.

Affinity Purified
Purified by affinity chromatography.

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Small volumes of anti-AVPR1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. AVPR1B expression has been documented in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.

Antibodies; Abs to Receptors

Western Blot (WB)

Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:32,000

46,971 Da[Similar Products]

arginine vasopressin receptor 1B

vasopressin V1b receptor; V1bR; AVPR V3; AVPR V1b; OTTHUMP00000034344; vasopressin V3 receptor; arginine vasopressin receptor 3; antidiuretic hormone receptor 1B; pituitary vasopressin receptor 3

Vasopressin V1b receptor

AVPR3; VPR3??[Similar Products]

V1BR_HUMAN

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq]

AVPR1B: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: integral to plasma membrane; plasma membrane; endosome

Molecular Function: protein kinase C binding; peptide binding; vasopressin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; regulation of systemic arterial blood pressure by vasopressin; phospholipase C activation; positive regulation of vasoconstriction; cellular response to hormone stimulus

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