Full Product Name
B3A2 Polyclonal Antibody
Product Synonym Names
Anion exchange protein 2; AE 2; Anion exchanger 2; Non-erythroid band 3-like protein; BND3L; Solute carrier family 4 member 2; SLC4A2; AE2; EPB3L1; HKB3; MPB3L
Product Gene Name
anti-B3A2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P04920
Species Reactivity
Human, Mouse
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Immunogen
Synthesized peptide derived from human protein. at AA range: 830-910
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-B3A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-B3A2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-B3A2 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for B3A2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001186621.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001199692.2
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UniProt Primary Accession #
P04920
[Other Products]
UniProt Secondary Accession #
Q45EY5; Q969L3; B2R6T0; B4DIT0; D3DX05; F8W682[Other Products]
UniProt Related Accession #
P04920[Other Products]
NCBI Official Full Name
anion exchange protein 2 isoform 1
NCBI Official Synonym Full Names
solute carrier family 4 member 2
NCBI Official Symbol
SLC4A2??[Similar Products]
NCBI Official Synonym Symbols
AE2; HKB3; BND3L; NBND3; EPB3L1
??[Similar Products]
NCBI Protein Information
anion exchange protein 2
UniProt Protein Name
Anion exchange protein 2
UniProt Synonym Protein Names
Non-erythroid band 3-like protein; BND3L; Solute carrier family 4 member 2
UniProt Gene Name
SLC4A2??[Similar Products]
UniProt Synonym Gene Names
AE2; EPB3L1; HKB3; MPB3L; AE 2; Anion exchanger 2; BND3L??[Similar Products]
NCBI Summary for B3A2
This gene encodes a member of the anion exchanger family of membrane transport proteins. The encoded protein regulates intracellular pH, biliary bicarbonate secretion, and chloride uptake. Reduced expression of this gene may be associated with primary biliary cirrhosis (PBC) in human patients, while differential expression of this gene may be associated with malignant hepatocellular carcinoma, colon and gastric cancers. [provided by RefSeq, Nov 2016]
UniProt Comments for B3A2
Plasma membrane anion exchange protein of wide distribution.
Research Articles on B3A2
1. To match the stimulatory effect on acid uptake, cell-to-cell coupling in NHDF-Ad and CCD-112-CoN cells was strengthened with TGFbeta1.Importantly, the activities of stromal AE2 and connexin-43 do not place an energetic burden on cancer cells, allowing resources to be diverted for other activities
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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