Full Product Name
DPP8 Antibody
Product Synonym Names
DP8; DPRP1; FLJ14920; FLJ20283; MGC26191; MSTP141
Product Gene Name
anti-DPP8 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of DPP8
Calculated Molecular Weight: 847aa; 97kd
Observed Molecular Weight: 75-83kd
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68349
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-DPP8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-DPP8 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-DPP8 antibody
WB: 1:200-1:2000
IHC: 1:50-1:200
Testing Data of anti-DPP8 antibody
NCBI/Uniprot data below describe general gene information for DPP8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_932065.1
[Other Products]
NCBI GenBank Nucleotide #
NM_197961.2
[Other Products]
UniProt Secondary Accession #
Q7Z4C8; Q7Z4D3; Q7Z4E1; Q8IWG7; Q8NEM5; Q96JX1; Q9HBM2; Q9HBM3; Q9HBM4; Q9HBM5; Q9NXF4[Other Products]
UniProt Related Accession #
Q6V1X1[Other Products]
Molecular Weight
83,398 Da
NCBI Official Full Name
dipeptidyl peptidase 8 isoform 4
NCBI Official Synonym Full Names
dipeptidyl-peptidase 8
NCBI Official Symbol
DPP8??[Similar Products]
NCBI Official Synonym Symbols
DP8; DPRP1; MSTP141
??[Similar Products]
NCBI Protein Information
dipeptidyl peptidase 8; DPP VIII; DPRP-1; dipeptidyl peptidase IV-related protein 1; dipeptidyl peptidase IV-related protein-1; dipeptidyl peptidase VIII; dipeptidylpeptidase 8; prolyl dipeptidase DPP8
UniProt Protein Name
Dipeptidyl peptidase 8
UniProt Synonym Protein Names
Dipeptidyl peptidase IV-related protein 1; DPRP-1; Dipeptidyl peptidase VIII; DPP VIII; Prolyl dipeptidase DPP8
Protein Family
Dipeptidyl peptidase
UniProt Gene Name
DPP8??[Similar Products]
UniProt Synonym Gene Names
DPRP1; DP8; DPRP-1; DPP VIII??[Similar Products]
UniProt Entry Name
DPP8_HUMAN
NCBI Summary for DPP8
This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for DPP8
DPP8: Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function. Belongs to the peptidase S9B family. DPPIV subfamily. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.14.5; Protease
Chromosomal Location of Human Ortholog: 15q22
Cellular Component: nucleoplasm; membrane; cytoplasm
Molecular Function: dipeptidyl-peptidase activity; serine-type peptidase activity
Biological Process: immune response; proteolysis
Research Articles on DPP8
1. The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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