Full Product Name
TCN2 Polyclonal Antibody
Product Synonym Names
D22S676; D22S750; II; Macrocytic anemia; OTTHUMP00000199117; OTTHUMP00000199118; OTTHUMP00000199119; TC; TC II; TC II deficiency; TC-2; TC2; TCII; TCN2; TCN2 deficiency; TCO2; Transcobalamin 2; Transcobalamin 2 deficiency; Transcobalamin II; Transcobalamin II; macrocytic anemia; Transcobalamin-2; Vitamin B12 binding protein 2
Product Gene Name
anti-TCN2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P20062
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1 mg/mL (lot specific)
Immunogen
Recombinant protein of human TCN2
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-TCN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TCN2 antibody
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-TCN2 antibody
Cardiovascular; Metabolism; Signal Transduction
Applications Tested/Suitable for anti-TCN2 antibody
Western Blot (WB)
Application Notes for anti-TCN2 antibody
WB: 1:500-1:2000
Western Blot (WB) of anti-TCN2 antibody
Western blot analysis of extracts of various cell lines, using TCN2 antibody.
NCBI/Uniprot data below describe general gene information for TCN2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000346.2
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NCBI GenBank Nucleotide #
NM_000355.3
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UniProt Primary Accession #
P20062
[Other Products]
UniProt Secondary Accession #
Q96FD4; Q9BVI8; Q9UCI5; Q9UCI6; Q9UDM0[Other Products]
UniProt Related Accession #
P20062[Other Products]
Molecular Weight
Calculated: 44kDa; 47kDa
Observed: 54kDa
NCBI Official Full Name
transcobalamin-2 isoform 1
NCBI Official Synonym Full Names
transcobalamin 2
NCBI Official Symbol
TCN2??[Similar Products]
NCBI Official Synonym Symbols
II; TC; TC2; TC-2; TCII; TC II; D22S676; D22S750
??[Similar Products]
NCBI Protein Information
transcobalamin-2
UniProt Protein Name
Transcobalamin-2
UniProt Synonym Protein Names
Transcobalamin II; TC II; TCII
Protein Family
Transcobalamin
UniProt Gene Name
TCN2??[Similar Products]
UniProt Synonym Gene Names
TC2; TC-2; TC II; TCII??[Similar Products]
NCBI Summary for TCN2
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
UniProt Comments for TCN2
Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells.
Research Articles on TCN2
1. 12 articles were included in this study. The pooled results did not reveal a significant association of the MTRR A66G polymorphism (G vs. A: OR = 0.99, 95% CI = 0.82-1.18, p = 0.72) with Nonsyndromic Cleft Lip With or Without Cleft Palate risk
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
