Product Name
Acid-sensing ion channel 3 (ASIC3), Polyclonal Antibody
Full Product Name
Acid-sensing ion channel 3 Polyclonal Antibody
Product Synonym Names
Amiloride-sensitive cation channel 3 Neuronal amiloride-sensitive cation channel 3 Testis sodium channel 1 ASIC3; ACCN3; SLNAC1; TNAC1
Product Gene Name
anti-ASIC3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9UHC3
Specificity
The antibody detects endogenous level of total Acid-sensing ion channel 3 polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (lot specific)
Immunogen
Recombinant Human Acid-sensing ion channel 3 protein
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-ASIC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ASIC3 antibody
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.
Product Categories/Family for anti-ASIC3 antibody
Total protein Ab
Applications Tested/Suitable for anti-ASIC3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ASIC3 antibody
Western Blot: 1:500 - 1:1000
Western Blot (WB) of anti-ASIC3 antibody
All lanes: PICK1 antibody at 2ug/ml+mouse brain tissue
NCBI/Uniprot data below describe general gene information for ASIC3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004760.1
[Other Products]
NCBI GenBank Nucleotide #
NM_004769.3
[Other Products]
UniProt Primary Accession #
Q9UHC3
[Other Products]
UniProt Secondary Accession #
O60263; O75906; Q59FN9; Q9UER8; Q9UHC4; B2R9V0[Other Products]
UniProt Related Accession #
Q9UHC3[Other Products]
Molecular Weight
44,999 Da[Similar Products]
NCBI Official Full Name
acid-sensing ion channel 3 isoform a
NCBI Official Synonym Full Names
acid sensing ion channel subunit 3
NCBI Official Symbol
ASIC3??[Similar Products]
NCBI Official Synonym Symbols
ACCN3; TNaC1; DRASIC; SLNAC1
??[Similar Products]
NCBI Protein Information
acid-sensing ion channel 3
UniProt Protein Name
Acid-sensing ion channel 3
UniProt Synonym Protein Names
Amiloride-sensitive cation channel 3; Neuronal amiloride-sensitive cation channel 3; Testis sodium channel 1; hTNaC1
Protein Family
Acid-sensing ion channel
UniProt Gene Name
ASIC3??[Similar Products]
UniProt Synonym Gene Names
ACCN3; SLNAC1; TNAC1; ASIC3; hASIC3; hTNaC1??[Similar Products]
UniProt Entry Name
ASIC3_HUMAN
UniProt Comments for ASIC3
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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