Product Name
Filamin (FLNA), Native Protein
Popular Item
Full Product Name
Filamin protein (Chicken)
Product Gene Name
FLNA native protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q90WF1
Purity/Purification
>90% by SDS-PAGE analysis
Form/Format
Lyophilized; reconstitute with 250ul Laemmli buffer or 9M urea buffer. Final solution contains 20mM Tris/acetate buffer pH 7.6, 0.1mM EDTA, 2mM DTT and 20mM NaCl. Protein concentration = 1.0 mg/ml (according to Bradford)
Concentration
250ug, lyophilzed (lot specific)
Source Note
Chicken gizzard
Biological Significance
Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.
Grade
Filamin, purified polypeptide
Biohazard
Not for human use, use normal laboratory precautions when handling reagent. For research purposes only.
Additional Remarks
Application: Protein standard in 1D and 2D SDS-gel electrophoresis Immunoassay, antigen for immunization. Isoelectric point: p1 6.4
Preparation and Storage
Ships ambient or refrigerated. Store lyophilzed product at 4 degree C. After reconstitution, aliquot and freeze at -20 degree C. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of FLNA native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FLNA native protein
Highly purified Filamin protein
Product Categories/Family for FLNA native protein
Cell Biology ; Native Protein
Applications Tested/Suitable for FLNA native protein
User optimized
NCBI/Uniprot data below describe general gene information for FLNA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_989905.1
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NCBI GenBank Nucleotide #
NM_204574.1
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UniProt Primary Accession #
Q90WF1
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NCBI Official Full Name
filamin-A
NCBI Official Synonym Full Names
filamin A, alpha
NCBI Official Symbol
FLNA??[Similar Products]
NCBI Official Synonym Symbols
filamin-A
??[Similar Products]
NCBI Protein Information
filamin-A
UniProt Protein Name
Filamin
UniProt Synonym Protein Names
Filamin
UniProt Entry Name
Q90WF1_CHICK
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
