Human FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) ELISA kit; FP634; H17; ; FAD-dependent oxidoreductase domain containing 1

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of FOXRED1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9335510 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the FAD-dependent oxidoreductase domain containing 1 (FOXRED1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FOXRED1. The ELISA analytical biochemical technique of the MBS9335510 kit is based on FOXRED1 antibody-FOXRED1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FOXRED1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FOXRED1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

53,812 Da

FAD-dependent oxidoreductase domain containing 1

FAD-dependent oxidoreductase domain-containing protein 1

FAD-dependent oxidoreductase domain-containing protein 1

FP634??[Similar Products]

FXRD1_HUMAN

This gene encodes a protein that contains a FAD-dependent oxidoreductase domain. The encoded protein is localized to the mitochondria and may function as a chaperone protein required for the function of mitochondrial complex I. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

FOXRED1: Defects in FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D). A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations from lethal neonatal disease to *****-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q24.2

Cellular Component: mitochondrion; integral to membrane

Molecular Function: oxidoreductase activity

Disease: Leigh Syndrome; Mitochondrial Complex I Deficiency

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