Product Name
FOXRED1, Polyclonal Antibody
Full Product Name
FOXRED1 (FAD-dependent Oxidoreductase Domain-containing Protein 1, FP634, H17)
Product Synonym Names
Anti -FOXRED1 (FAD-dependent Oxidoreductase Domain-containing Protein 1, FP634, H17)
Product Gene Name
anti-FOXRED1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
MIRRVLPHGM GRGLLTRRPG TRRGGFSLDW DGKVSEIKKK IKSILPGRSC DLLQDTSHLP PEHSDVVIVG GGVLGLSVAY WLKKLESRRG AIRVLVVERD HTYSQASTGL SVGGICQQFS LPENIQLSLF SASFLRNINE YLAVVDAPPL DLRFNPSGYL LLASEKDAAA MESNVKVQRQ EGAKVSLMSP DQLRNKFPWI NTEGVALASY GMEDEGWFDP WCLLQGLRRK VQSLGVLFCQ GEVTRFVSSS QRMLTTDDKA VVLKRIHEVH VKMDRSLEYQ PVECAIVINA AGAWSAQIAA LAGVGEGPPG TLQGTKLPVE PRKRYVYVWH CPQGPGLETP LVADTSGAYF RREGLGSNYL GGRSPTEQEE PDPANLEVDH DFFQDKVWPH LALRVPAFET LKVQSAWAGY YDYNTFDQNG VVGPHPLVVN MYFATGFSGH GLQQAPGIGR AVAEMVLKGR FQTIDLSPFL FTRFYLGEKI QENNII
Chromosome Location
Chromosome: 11; NC_000011.9 (126138935..126148027). Location: 11q24.2
3D Structure
ModBase 3D Structure for Q96CU9
Specificity
Recognizes human FOXRED1.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Immunogen
Full length human FOXRED1, aa1-486 (NP_060017.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-FOXRED1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-FOXRED1 antibody
Antibodies; Abs to Transcription Factors
Applications Tested/Suitable for anti-FOXRED1 antibody
Western Blot (WB)
Application Notes for anti-FOXRED1 antibody
Suitable for use in Western Blot.
NCBI/Uniprot data below describe general gene information for FOXRED1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_060017.1
[Other Products]
NCBI GenBank Nucleotide #
NM_017547.3
[Other Products]
UniProt Primary Accession #
Q96CU9
[Other Products]
UniProt Secondary Accession #
Q71MG0; Q9BU39; Q9UKY9; B3KN84; B4DHU2[Other Products]
UniProt Related Accession #
Q96CU9[Other Products]
Molecular Weight
53,812 Da[Similar Products]
NCBI Official Full Name
FAD-dependent oxidoreductase domain-containing protein 1
NCBI Official Synonym Full Names
FAD-dependent oxidoreductase domain containing 1
NCBI Official Symbol
FOXRED1??[Similar Products]
NCBI Official Synonym Symbols
H17; FP634
??[Similar Products]
NCBI Protein Information
FAD-dependent oxidoreductase domain-containing protein 1
UniProt Protein Name
FAD-dependent oxidoreductase domain-containing protein 1
Protein Family
FAD-dependent oxidoreductase domain-containing protein
UniProt Gene Name
FOXRED1??[Similar Products]
UniProt Entry Name
FXRD1_HUMAN
NCBI Summary for FOXRED1
This gene encodes a protein that contains a FAD-dependent oxidoreductase domain. The encoded protein is localized to the mitochondria and may function as a chaperone protein required for the function of mitochondrial complex I. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
UniProt Comments for FOXRED1
Cofactor: FAD
By similarity.
Subcellular location: Membrane; Single-pass membrane protein
Potential.
Involvement in disease: Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations from lethal neonatal disease to *****-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.8
Research Articles on FOXRED1
1. Mutations in FOXRED1 are associated with complex I deficiency.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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