Full Product Name
Barx1 (BarH Family Homeodomain Transcription Factor)
Product Synonym Names
Anti -Barx1 (BarH Family Homeodomain Transcription Factor)
Product Gene Name
anti-BARX1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
chromosome: 9; Location: 9q12
3D Structure
ModBase 3D Structure for Q9HBU1
Species Reactivity
Human, Rodent
Specificity
Recognizes human Barx1 (BarH Family Homeodomain Transcription Factor). Species Crossreactivity: rodent.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS, sodium azide, 40% glycerol.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-BARX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-BARX1 antibody
Antibodies; Abs to Transcription Factors
Applications Tested/Suitable for anti-BARX1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-BARX1 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA (serum titer): 1:75,000.
Western Blot:
Human stomach and pancreas: 30, 32 kD
HepG2: 34. 36kD
Rat pancreas: 45, 55kD
Mouse pancreas: 23,29kD
NCBI/Uniprot data below describe general gene information for BARX1. It may not necessarily be applicable to this product.
UniProt Primary Accession #
Q9HBU1
[Other Products]
UniProt Secondary Accession #
Q6P2R4; Q96GH8[Other Products]
UniProt Related Accession #
Q9HBU1[Other Products]
Molecular Weight
24.06kD[Similar Products]
NCBI Official Full Name
BARX homeobox 1
NCBI Official Synonym Full Names
BARX homeobox 1
NCBI Official Symbol
BARX1??[Similar Products]
NCBI Official Synonym Symbols
BARX1
??[Similar Products]
NCBI Protein Information
homeobox protein BarH-like 1; OTTHUMP00000197307; BarH-like homeobox 1
UniProt Protein Name
Homeobox protein BarH-like 1
Protein Family
Homeobox protein
UniProt Gene Name
BARX1??[Similar Products]
UniProt Entry Name
BARX1_HUMAN
NCBI Summary for BARX1
This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq]
UniProt Comments for BARX1
BARX1: Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity. Binds to a regulatory module of the NCAM promoter. Belongs to the BAR homeobox family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 9q12
Cellular Component: nucleus
Molecular Function: sequence-specific DNA binding; transcription factor activity
Biological Process: anterior/posterior pattern formation; spleen development; negative regulation of Wnt receptor signaling pathway; epithelial cell differentiation; transcription, DNA-dependent; cell-cell signaling; regulation of transcription, DNA-dependent
Research Articles on BARX1
1. Regional expression of barx1 was observed in epithelium before mixed dentition, while during mixed dentition gene appeared in hyaline cartilage. Expression of barx1 appears in cleft lip palate affected structures mainly in mixed dentition.
2. Observational study of gene-disease association. (HuGE Navigator)
3. PITX2, BARX1, and FOXC1 mutations were absent in De Hauwere syndrome and suggest that De Hauwere syndrome is caused by a different gene.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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