Sonic hedgehog protein A; SHHA; VHH-1; Sonic hedgehog protein A N-product; Sonic hedgehog protein A C-product; shha; shh; vhh1

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

This shha antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 151-162 amino acids from the Central region of DANRE shha.

Purified Rabbit Polyclonal Antibody (Pab)

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Vial Concentration: 0.5 (lot specific)

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Small volumes of anti-shha antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).

Crown Antibodies

Western Blot (WB), ELISA (EIA)

WB~~1:1000

Shha Antibody (Center) western blot analysis in zebrafish brain tissue lysate (35ug/lane). This demonstrates that the (DANRE) shha antibody detected zebrafish shha protein (arrow).

46403

sonic hedgehog a

sonic hedgehog protein A

Sonic hedgehog protein A

shh; vhh1; SHHA??[Similar Products]

SHH_DANRE

Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO ().

Roelink H.,et al.Cell 76:761-775(1994).
Ekker S.C.,et al.Curr. Biol. 5:944-955(1995).
Fietz M.J.,et al.Development Suppl. 120:43-51(1994).
Muller F.,et al.Development 126:2103-2116(1999).
Zardoya R.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:13036-13041(1996).

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.