Product Name
SETBP1, Blocking Peptide
Full Product Name
SETBP1 Peptide - middle region
Product Gene Name
SETBP1 blocking peptide
[Similar Products]
Product Synonym Gene Name
KIAA0437; SEB[Similar Products]
SETBP1 peptide (MBS3229452) is used for blocking the activity of SETBP1 antibody (MBS3204485)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9Y6X0
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of SETBP1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SETBP1 blocking peptide
This is a synthetic peptide designed for use in combination with anti-SETBP1 antibody made
Target Description: The function of this protein remains unknown.
Product Categories/Family for SETBP1 blocking peptide
Peptide
Applications Tested/Suitable for SETBP1 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for SETBP1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_056374
[Other Products]
NCBI GenBank Nucleotide #
NM_015559
[Other Products]
UniProt Primary Accession #
Q9Y6X0
[Other Products]
UniProt Related Accession #
Q9Y6X0[Other Products]
NCBI Official Full Name
SET-binding protein isoform a
NCBI Official Synonym Full Names
SET binding protein 1
NCBI Official Symbol
SETBP1??[Similar Products]
NCBI Official Synonym Symbols
SEB; MRD29
??[Similar Products]
NCBI Protein Information
SET-binding protein
UniProt Protein Name
SET-binding protein
Protein Family
SET-binding protein
UniProt Gene Name
SETBP1??[Similar Products]
UniProt Synonym Gene Names
KIAA0437; SEB??[Similar Products]
NCBI Summary for SETBP1
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
UniProt Comments for SETBP1
SETBP1: Defects in SETBP1 are the cause of Schinzel-Giedion midface retraction syndrome (SGMFS). It is a disorder characterized by severe mental retardation, distinctive facial features, and multiple congenital malformations including skeletal abnormalities, genitourinary and renal malformations, cardiac defects, as well as a higher-than-normal prevalence of tumors, notably neuroepithelial neoplasia. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 18q12.3
Molecular Function: protein binding
Disease: Mental Retardation, Autosomal Dominant 29; Schinzel-giedion Midface Retraction Syndrome
Research Articles on SETBP1
1. CIP2A- and SETBP1-mediated PP2A inhibition reveals AKT S473 phosphorylation to be a new biomarker in AML.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
