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DLX1, Polyclonal Antibody

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DLX1, Polyclonal Antibody


DLX1, Polyclonal Antibody  的詳細介紹
Product Name

DLX1, Polyclonal Antibody

Full Product Name

DLX1 Antibody

Product Synonym Names
DLX1, Homeobox protein DLX 1, distal less homeobox 1
Product Gene Name

anti-DLX1 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
600029
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of DLX1
Calculated Molecular Weight: 255aa; 27kd
Observed Molecular Weight: 27kd
Buffer
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-DLX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-DLX1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-DLX1 antibody
WB: 1:200-1:2000

Testing Data of anti-DLX1 antibody
anti-DLX1 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for DLX1. It may not necessarily be applicable to this product.
NCBI GI #
608785255
NCBI GeneID
1745
NCBI Accession #
AHW56464.1 [Other Products]
UniProt Secondary Accession #
Q53ZU4; Q7Z724; Q8IYB2; D3DPD7[Other Products]
UniProt Related Accession #
P56177[Other Products]
Molecular Weight
13,521 Da
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NCBI Official Full Name
distal-less homeobox 1 isoform A, partial
NCBI Official Synonym Full Names
distal-less homeobox 1
NCBI Official Symbol
DLX1??[Similar Products]
NCBI Protein Information
homeobox protein DLX-1; distal-less homeo box 1
UniProt Protein Name
Homeobox protein DLX-1
Protein Family
Homeobox protein
UniProt Gene Name
DLX1??[Similar Products]
UniProt Entry Name
DLX1_HUMAN
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NCBI Summary for DLX1
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for DLX1
DLX1: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions. Belongs to the distal-less homeobox family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 2q32

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding; chromatin binding

Biological Process: negative regulation of oligodendrocyte differentiation; cerebral cortex GABAergic interneuron fate commitment; embryonic skeletal development; hippocampus development; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment; negative regulation of Notch signaling pathway; subpallium development; negative regulation of neuron apoptosis; negative regulation of transcription from RNA polymerase II promoter; proximal/distal pattern formation; odontogenesis of dentine-containing teeth
Research Articles on DLX1
1. The study data demonstrate an association between SNP rs7888172 of the DLX1 gene and non-syndromic hypodontia in Chinese Han individuals.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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