Full Product Name
DLX1 Antibody
Product Synonym Names
DLX1, Homeobox protein DLX 1, distal less homeobox 1
Product Gene Name
anti-DLX1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of DLX1
Calculated Molecular Weight: 255aa; 27kd
Observed Molecular Weight: 27kd
Buffer
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-DLX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-DLX1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-DLX1 antibody
WB: 1:200-1:2000
Testing Data of anti-DLX1 antibody
NCBI/Uniprot data below describe general gene information for DLX1. It may not necessarily be applicable to this product.
NCBI Accession #
AHW56464.1
[Other Products]
UniProt Secondary Accession #
Q53ZU4; Q7Z724; Q8IYB2; D3DPD7[Other Products]
UniProt Related Accession #
P56177[Other Products]
Molecular Weight
13,521 Da
NCBI Official Full Name
distal-less homeobox 1 isoform A, partial
NCBI Official Synonym Full Names
distal-less homeobox 1
NCBI Official Symbol
DLX1??[Similar Products]
NCBI Protein Information
homeobox protein DLX-1; distal-less homeo box 1
UniProt Protein Name
Homeobox protein DLX-1
Protein Family
Homeobox protein
UniProt Gene Name
DLX1??[Similar Products]
UniProt Entry Name
DLX1_HUMAN
NCBI Summary for DLX1
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for DLX1
DLX1: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions. Belongs to the distal-less homeobox family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 2q32
Cellular Component: nucleus
Molecular Function: sequence-specific DNA binding; chromatin binding
Biological Process: negative regulation of oligodendrocyte differentiation; cerebral cortex GABAergic interneuron fate commitment; embryonic skeletal development; hippocampus development; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment; negative regulation of Notch signaling pathway; subpallium development; negative regulation of neuron apoptosis; negative regulation of transcription from RNA polymerase II promoter; proximal/distal pattern formation; odontogenesis of dentine-containing teeth
Research Articles on DLX1
1. The study data demonstrate an association between SNP rs7888172 of the DLX1 gene and non-syndromic hypodontia in Chinese Han individuals.
Precautions
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