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DLX1, Polyclonal Antibody

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產品名稱: DLX1, Polyclonal Antibody
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DLX1, Polyclonal Antibody


DLX1, Polyclonal Antibody  的詳細介紹
Product Name

DLX1, Polyclonal Antibody

Full Product Name

DLX1 antibody - N-terminal region

Product Gene Name

anti-DLX1 antibody

[Similar Products]
Antibody/Peptide Pairs
DLX1 peptide (MBS3229937) is used for blocking the activity of DLX1 antibody (MBS3204971)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence
Synthetic peptide located within the following region: MTMTTMPESL NSPVSGKAVF MEFGPPNQQM SPSPMSHGHY SMHCLHSAGH
OMIM
600029
3D Structure
ModBase 3D Structure for P56177
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human DLX1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-DLX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-DLX1 antibody
This is a rabbit polyclonal antibody against DLX1. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: DLX1 is a member of a homeobox transcription factor family. It is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. DLX1 may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described.
Product Categories/Family for anti-DLX1 antibody
Polyclonal; Transcription Factor; Transcription Regulation; Chromatin & Nuclear Signaling; Neuroscience; Signal Transduction; Various; Transcription Factors; Cell Differentiation;
Applications Tested/Suitable for anti-DLX1 antibody
Western Blot (WB)

Western Blot (WB) of anti-DLX1 antibody
WB Suggested Anti-DLX1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: THP-1 cell lysate
anti-DLX1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for DLX1. It may not necessarily be applicable to this product.
NCBI GI #
64225290
NCBI GeneID
1745
NCBI Accession #
NP_835221 [Other Products]
NCBI GenBank Nucleotide #
NM_178120 [Other Products]
UniProt Primary Accession #
P56177 [Other Products]
UniProt Related Accession #
P56177[Other Products]
Molecular Weight
27kDa
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NCBI Official Full Name
homeobox protein DLX-1 isoform 1
NCBI Official Synonym Full Names
distal-less homeobox 1
NCBI Official Symbol
DLX1??[Similar Products]
NCBI Protein Information
homeobox protein DLX-1
UniProt Protein Name
Homeobox protein DLX-1
Protein Family
Homeobox protein
UniProt Gene Name
DLX1??[Similar Products]
UniProt Entry Name
DLX1_HUMAN
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NCBI Summary for DLX1
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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Research Articles on DLX1
1. observations suggest that altered DLX1 methylation and expression contribute to pathogenesis of PSP by influencing MAPT.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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