Product Name
Collagen alpha-2 (IX) chain (COL9A2), Recombinant Protein
Full Product Name
Recombinant Human Collagen alpha-2 (IX) chain (COL9A2)
Product Gene Name
COL9A2 recombinant protein
[Similar Products]
Product Synonym Gene Name
COL9A2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
24-689aa, Full Length of Mature Protein
Sequence
QIRGPPGERG PPGPPGPPGV PGSDGIDGDN GPPGKAGPPG PKGEPGKAGP DGPDGKPGID GLTGAKGEPG PMGIPGVKGQ PGLPGPPGLP GPGFAGPPGP PGPVGLPGEI GIRGPKGDPG PDGPSGPPGP PGKPGRPGTI QGLEGSADFL CPTNCPPGMK GPPGLQGVKG HAGKRGILGD PGHQGKPGPK GDVGASGEQG IPGPPGPQGI RGYPGMAGPK GETGPHGYKG MVGAIGATGP PGEEGPRGPP GRAGEKGDEG SPGIRGPQGI TGPKGATGPP GINGKDGTPG TPGMKGSAGQ AGQPGSPGHQ GLAGVPGQPG TKGGPGDQGE PGPQGLPGFS GPPGKEGEPG PRGEIGPQGI MGQKGDQGER GPVGQPGPQG RQGPKGEQGP PGIPGPQGLP GVKGDKGSPG KTGPRGKVGD PGVAGLPGEK GEKGESGEPG PKGQQGVRGE PGYPGPSGDA GAPGVQGYPG PPGPRGLAGN RGVPGQPGRQ GVEGRDATDQ HIVDVALKML QEQLAEVAVS AKREALGAVG MMGPPGPPGP PGYPGKQGPH GHPGPRGVPG IVGAVGQIGN TGPKGKRGEK GDPGEVGRGH PGMPGPPGIP GLPGRPGQAI NGKDGDRGSP GAPGEAGRPG LPGPVGLPGF CEPAACLGAS AYASARLTEP GSIKGP
3D Structure
ModBase 3D Structure for Q14055
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of COL9A2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
COL9A2 recombinant protein
This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. This chain is unusual in that, unlike the other two type IX alpha chains, it contains a covalently attached glycosaminoglycan side chain. Mutations in this gene are associated with multiple epiphyseal dysplasia.
NCBI/Uniprot data below describe general gene information for COL9A2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001843.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001852.3
[Other Products]
UniProt Primary Accession #
Q14055
[Other Products]
UniProt Secondary Accession #
B2RMP9[Other Products]
UniProt Related Accession #
Q14055[Other Products]
Molecular Weight
65,131 Da
NCBI Official Full Name
collagen alpha-2(IX) chain
NCBI Official Synonym Full Names
collagen type IX alpha 2 chain
NCBI Official Symbol
COL9A2??[Similar Products]
NCBI Official Synonym Symbols
MED; EDM2; STL5; DJ39G22.4
??[Similar Products]
NCBI Protein Information
collagen alpha-2(IX) chain
UniProt Protein Name
Collagen alpha-2(IX) chain
UniProt Gene Name
COL9A2??[Similar Products]
NCBI Summary for COL9A2
This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. This chain is unusual in that, unlike the other two type IX alpha chains, it contains a covalently attached glycosaminoglycan side chain. Mutations in this gene are associated with multiple epiphyseal dysplasia. [provided by RefSeq, Jul 2008]
UniProt Comments for COL9A2
Structural component of hyaline cartilage and vitreous of the eye.
Research Articles on COL9A2
1. Study provides evidence that the COL9A2 Gln326Arg polymorphism contributes to the development of intervertebral disc disease in the Chinese population.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
