Product Name
Stimulated by retinoic acid gene 6 protein homolog (STRA6), Recombinant Protein
Full Product Name
Recombinant Pongo abelii Stimulated by retinoic acid gene 6 protein homolog (STRA6), partial
Product Gene Name
STRA6 recombinant protein
[Similar Products]
Product Synonym Gene Name
STRA6[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q5R7B4
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Pongo abelii (Sumatran orangutan)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of STRA6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for STRA6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001127142.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001133670.1
[Other Products]
UniProt Primary Accession #
Q5R7B4
[Other Products]
UniProt Secondary Accession #
Q5RFR1[Other Products]
UniProt Related Accession #
Q5R7B4[Other Products]
Molecular Weight
72,712 Da
NCBI Official Full Name
receptor for retinol uptake STRA6
NCBI Official Symbol
STRA6??[Similar Products]
NCBI Protein Information
receptor for retinol uptake STRA6
UniProt Protein Name
Receptor for retinol uptake STRA6
UniProt Synonym Protein Names
Retinol-binding protein receptor STRA6; Stimulated by retinoic acid gene 6 protein homolog
Protein Family
Stimulated by retinoic acid gene 6 protein
UniProt Gene Name
STRA6??[Similar Products]
UniProt Comments for STRA6
Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin. Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid. STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency. Does not transport retinoic acid.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
