Stimulated by retinoic acid gene 6 protein homolog; STRA6

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit Ig

Rabbit

This STRA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-614 amino acids from the C-terminal region of human STRA6.

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Vial Concentration: 0.49 (lot specific)

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Small volumes of anti-STRA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

STRA6 is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9).

Developmental Biology; Metabolism; Signal Transduction

Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)

WB~~1:1000

Western blot analysis of STRA6 Antibody (C-term) in Hela cell line lysates (35ug/lane). UBAC1 (arrow) was detected using the purified Pab;

Western blot analysis of STRA6 Antibody (C-term) in mouse bladder tissue lysates (35ug/lane). STRA6 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human hepatocarcinoma with STRA6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

73503

stimulated by retinoic acid 6

stimulated by retinoic acid gene 6 protein homolog

Stimulated by retinoic acid gene 6 protein homolog

STRA6_HUMAN

Chassaing, N., et al. Hum. Mutat. 30 (5), E673-E681 (2009)
West, B., et al. Am. J. Med. Genet. A 149A (3), 539-542 (2009)
Kawaguchi, R., et al. J. Biol. Chem. 283(22):15160-15168(2008)
Isken, A., et al. Cell Metab. 7(3):258-268(2008)
White, T., et al. Mol. Vis. 14, 2458-2465 (2008)

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