Product Name
ALX homeobox protein 1 (Alx1), Recombinant Protein
Full Product Name
Recombinant Rat ALX homeobox protein 1 (Alx1)
Product Gene Name
Alx1 recombinant protein
[Similar Products]
Product Synonym Gene Name
Alx1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-326aa, full length protein
Sequence
MEFLSEKFAL KSPPSKNSDF YMGTGGALEH VMETLDNESF YGKATAGKCV QAFGPLPRAE HHVRLDRTSP CQDSSVNYGI TKVEGQPLHT ELNRAMDGCN NLRMSPVKGM PEKSELDELG DKCDSNVSSS KKRRHRTTFT SLQLEELEKV FQKTHYPDVY VREQLALRTE LTEARVQVWF QNRRAKWRKR ERYGQIQQAK SHFAATYDIS VLPRTDSYPQ IQNNLWAGNT SGGSVVTSCM LPRDASSCMT PYSHSPRTDS SYTGFSNHQN QFGHVPLNNF FTDSLLTGTT NGHAFETKPE FERRSSSIAV LRMKAKEHTA NISWAM
3D Structure
ModBase 3D Structure for Q63087
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Alx1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Alx1 recombinant protein
The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly.
NCBI/Uniprot data below describe general gene information for Alx1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_037053.1
[Other Products]
NCBI GenBank Nucleotide #
NM_012921.1
[Other Products]
UniProt Primary Accession #
Q63087
[Other Products]
UniProt Related Accession #
Q63087[Other Products]
Molecular Weight
31,638 Da
NCBI Official Full Name
ALX homeobox protein 1
NCBI Official Synonym Full Names
ALX homeobox 1
NCBI Official Symbol
Alx1??[Similar Products]
NCBI Official Synonym Symbols
Cart1; CART1X
??[Similar Products]
NCBI Protein Information
ALX homeobox protein 1
UniProt Protein Name
ALX homeobox protein 1
UniProt Synonym Protein Names
Cartilage homeoprotein 1
Protein Family
ALX homeobox protein
UniProt Gene Name
Alx1??[Similar Products]
UniProt Synonym Gene Names
CART-1??[Similar Products]
NCBI Summary for Alx1
homeodomain transcription factor that may play a role in chondrocyte differentiation [RGD, Feb 2006]
UniProt Comments for Alx1
Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes (PubMed:12929931). Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures (). Early on in development, it plays a role in forebrain mesenchyme survival (). May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1 ().
Research Articles on Alx1
1. p300/CBP stimulate Cart1-dependent transcription activity, and this transactivation is inhibited by E1A and Tax, oncoproteins that suppress the activity of p300/CBP
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
