Full Product Name
Anti-TGFBI Antibody
Product Synonym Names
BIGH3; Transforming growth factor-beta-induced protein ig-h3; Beta ig-h3; Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP
Product Gene Name
anti-TGFBI antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q15582
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of TGFBI protein.
Purity/Purification
Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
Recombinant full length protein of human TGFBI
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-TGFBI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TGFBI antibody
Rabbit polyclonal antibody to TGFBI
Applications Tested/Suitable for anti-TGFBI antibody
Western Blot (WB)
Application Notes for anti-TGFBI antibody
WB: 1/500 - 1/2000
Western Blot (WB) of anti-TGFBI antibody
Western blot analysis of TGFBI expression in BXPC3 (A), mouse heart (B), rat kidney (C) whole cell lysates.
NCBI/Uniprot data below describe general gene information for TGFBI. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000349.1
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NCBI GenBank Nucleotide #
NM_000358.2
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UniProt Primary Accession #
Q15582
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UniProt Secondary Accession #
O14471; O14472; O14476; O43216; O43217; O43218; O43219; Q53XM1; D3DQB1[Other Products]
UniProt Related Accession #
Q15582[Other Products]
Molecular Weight
74,681 Da
NCBI Official Full Name
transforming growth factor-beta-induced protein ig-h3
NCBI Official Synonym Full Names
transforming growth factor beta induced
NCBI Official Symbol
TGFBI??[Similar Products]
NCBI Official Synonym Symbols
CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1
??[Similar Products]
NCBI Protein Information
transforming growth factor-beta-induced protein ig-h3
UniProt Protein Name
Transforming growth factor-beta-induced protein ig-h3
UniProt Synonym Protein Names
Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP
Protein Family
Transforming growth factor-beta-induced protein
UniProt Gene Name
TGFBI??[Similar Products]
UniProt Synonym Gene Names
BIGH3; Beta ig-h3; RGD-CAP??[Similar Products]
NCBI Summary for TGFBI
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]
UniProt Comments for TGFBI
Plays a role in cell adhesion (PubMed:8024701). May play a role in cell-collagen interactions ().
Research Articles on TGFBI
1. G in exon 12 that leads to (Leu558Arg) change at the protein level.">A novel heterozygous TGFBI mutation was identified in the proband, c.1673T>G in exon 12 that leads to (Leu558Arg) change at the protein level.
Precautions
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Disclaimer
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