Full Product Name
TGFBI antibody - C-terminal region
Product Gene Name
anti-TGFBI antibody
[Similar Products]
Product Synonym Gene Name
BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1[Similar Products]
Antibody/Peptide Pairs
TGFBI peptide (MBS3232253) is used for blocking the activity of TGFBI antibody (MBS3207288)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: LKNNVVSVNK EPVAEPDIMA TNGVVHVITN VLQPPANRPQ ERGDELADSA
3D Structure
ModBase 3D Structure for Q15582
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Protein A purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TGFBI
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-TGFBI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TGFBI antibody
This is a rabbit polyclonal antibody against TGFBI. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: TGFBI Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.
Product Categories/Family for anti-TGFBI antibody
Polyclonal; Transcription Factor; Signal Proteins; Chromatin & Nuclear Signaling; Disease Related; DNA/RNA/Protein Interactions;
Applications Tested/Suitable for anti-TGFBI antibody
Immunofluorescence (IF), Western Blot (WB)
Immunofluorescence (IF) of anti-TGFBI antibody
Species, Tissue/Cell Type:
Human Cornea tissue (epithelium and stroma)
Primary used and dilution: 1:400
Western Blot (WB) of anti-TGFBI antibody
Host: Rabbit
Target Name: TGFBI
Sample Type: Jurkat
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 2.5ug/mL
Peptide Concentration: 2.0ug/mL
Lysate Quantity: 25ug/lane
Gel Concentration: 12%
Western Blot (WB) of anti-TGFBI antibody
WB Suggested Anti-TGFBI Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysate
NCBI/Uniprot data below describe general gene information for TGFBI. It may not necessarily be applicable to this product.
NCBI Accession #
AAH26352
[Other Products]
NCBI GenBank Nucleotide #
NM_000358.3
[Other Products]
UniProt Primary Accession #
Q15582
[Other Products]
UniProt Related Accession #
Q15582[Other Products]
NCBI Official Full Name
transforming growth factor-beta-induced protein ig-h3
NCBI Official Synonym Full Names
transforming growth factor beta induced
NCBI Official Symbol
TGFBI??[Similar Products]
NCBI Official Synonym Symbols
CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1
??[Similar Products]
NCBI Protein Information
transforming growth factor-beta-induced protein ig-h3
UniProt Protein Name
Transforming growth factor-beta-induced protein ig-h3
UniProt Synonym Protein Names
Kerato-epithelin; RGD-containing collagen-associated protein
Protein Family
Transforming growth factor-beta-induced protein
UniProt Gene Name
TGFBI??[Similar Products]
UniProt Synonym Gene Names
BIGH3; Beta ig-h3; RGD-CAP??[Similar Products]
UniProt Entry Name
BGH3_HUMAN
NCBI Summary for TGFBI
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]
Research Articles on TGFBI
1. On 10 mug/ml periostin or TGFBI, more eosinophils adopted a flattened pancake morphology with dispersed granules and nuclear lobes, and slower migration. Conversion between acorn and pancake morphologies were observed. TGFBI or periostin supports two modes of migration by IL-5 family cytokine-activated eosinophils.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
