Product Name
TGFBI, cDNA Clone
Full Product Name
TGFBI cDNA Clone
Product Gene Name
TGFBI cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcgctct tcgtgcggct gctggctctc gccctggctc tggccctggg ccccgccgcg accctggcgg gtcccgccaa gtcgccctac cagctggtgc tgcagcacag caggctccgg ggccgccagc acggccccaa cgtgtgtgct gtgcagaagg ttattggcac taataggaag tacttcacca actgcaagca gtggtaccaa aggaaaatct gtggcaaatc aacagtcatc agctacgagt gctgtcctgg atatgaaaag gtccctgggg agaagggctg tccagcagcc ctaccactct caaaccttta cgagaccctg ggagtcgttg gatccaccac cactcagctg tacacggacc gcacggagaa gctgaggcct gagatggagg ggcccggcag cttcaccatc ttcgccccta gcaacgaggc ctgggcctcc ttgccagctg aagtgctgga ctccctggtc agcaatgtca acattgagct gctcaatgcc ctccgctacc atatggtggg caggcgagtc ctgactgatg agctgaaaca cggcatgacc ctcacctcta tgtaccagaa ttccaacatc cagatccacc actatcctaa tgggattgta actgtgaact gtgcccggct gctgaaagcc gaccaccatg caaccaacgg ggtggtgcac ctcatcgata aggtcatctc caccatcacc aacaacatcc agcagatcat tgagatcgag gacacctttg agacccttcg ggctgctgtg gctgcatcag ggctcaacac gatgcttgaa ggcaacggcc agtacacgct tttggccccg accaatgagg ccttcgagaa gatccctagt gagactttga accgtatcct gggcgaccca gaagccctga gagacctgct gaacaaccac atcttgaagt cagctatgtg tgctgaagcc atcgttgcgg ggctgtctgt ggagaccctg gagggcacga cactggaggt gggctgcagc ggggacatgc tcactatcaa cgggaaggcg atcatctcca ataaagacat cctagccacc aacggggtga tccactacat tgatgagcta ctcatcccag actcagccaa gacactattt gaattggctg cagagtctga tgtgtccaca gccattgacc ttttcagaca agccggcctc ggcaatcatc tctctggaag tgagcggttg accctcctgg ctcccctgaa ttctgtattc aaagatggaa cccctccaat tgatgcccat acaaggaatt tgcttcggaa ccacataatt aaagaccagc tggcctctaa gtatctgtac catggacaga ccctggaaac tctgggcggc aaaaaactga gagtttttgt ttatcgtaat agcctttgca ttgagaacag ctgcatcgcg gcccacgaca agagggggag gtacgggacc ctgttcacga tggaccgggt gctgaccccc ccaatgggga ctgtcatgga tgtcctgaag ggagacaatc gctttagcat gctggtagct gccatccagt ctgcaggact gacggagacc ctcaaccggg aaggagtcta cacagtcttc gctcccacaa atgaagcctt ccgagccctg ccaccaagag aacggagcag actcttggga gatgccaagg aacttgccaa catcctgaaa taccacattg gtgatgaaat cctggttagc ggaggcatcg gggccctggt gcggctaaag tctctccaag gtgacaagct ggaagtcagc ttgaaaaaca atgtggtgag tgtcaacaag gagcctgttg ccgagcctga catcatggcc acaaatggcg tggtccatgt catcaccaat gttctgcagc ctccagccaa cagacctcag gaaagagggg atgaacttgc agactctgcg cttgagatct tcaaacaagc atcagcgttt tccagggctt cccagaggtc tgtgcgacta gcccctgtct atcaaaagtt attagagagg atgaagcatt ag
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of TGFBI cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TGFBI. It may not necessarily be applicable to this product.
NCBI Accession #
BC004972
[Other Products]
UniProt Secondary Accession #
O14471; O14472; O14476; O43216; O43217; O43218; O43219; Q53XM1; D3DQB1[Other Products]
UniProt Related Accession #
Q15582[Other Products]
Molecular Weight
74,681 Da
NCBI Official Full Name
Homo sapiens transforming growth factor, beta-induced, 68kDa, mRNA
NCBI Official Synonym Full Names
transforming growth factor beta induced
NCBI Official Symbol
TGFBI??[Similar Products]
NCBI Official Synonym Symbols
CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1
??[Similar Products]
NCBI Protein Information
transforming growth factor-beta-induced protein ig-h3
UniProt Protein Name
Transforming growth factor-beta-induced protein ig-h3
UniProt Synonym Protein Names
Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP
Protein Family
Transforming growth factor-beta-induced protein
UniProt Gene Name
TGFBI??[Similar Products]
UniProt Synonym Gene Names
BIGH3; Beta ig-h3; RGD-CAP??[Similar Products]
UniProt Entry Name
BGH3_HUMAN
NCBI Summary for TGFBI
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]
UniProt Comments for TGFBI
betaIG-H3: Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation. By TGFB1. Highly expressed in the corneal epithelium.
Protein type: Extracellular matrix; Secreted; Secreted, signal peptide; Cell adhesion
Chromosomal Location of Human Ortholog: 5q31
Cellular Component: extracellular matrix; extracellular region; extracellular space; plasma membrane; proteinaceous extracellular matrix; trans-Golgi network
Molecular Function: collagen binding; protein binding
Biological Process: angiogenesis; cellular protein metabolic process; extracellular matrix organization and biogenesis; negative regulation of cell adhesion
Disease: Corneal Dystrophy Of Bowman Layer, Type I; Corneal Dystrophy Of Bowman Layer, Type Ii; Corneal Dystrophy, Avellino Type; Corneal Dystrophy, Epithelial Basement Membrane; Corneal Dystrophy, Groenouw Type I; Corneal Dystrophy, Lattice Type I; Corneal Dystrophy, Lattice Type Iiia
Research Articles on TGFBI
1. Vicenin-2 and scolymoside could be a potential therapeutic agent for treatment of various severe vascular inflammatory diseases via inhibition of the TGFBIp signaling pathway.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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