Product Name
MUC16, Polyclonal Antibody
Popular Item
Full Product Name
Goat anti-Rat MUC16, ID (Mucin 16, Cell Surface Associated)
Product Synonym Names
Anti -MUC16, ID (Mucin 16, Cell Surface Associated)
Product Gene Name
anti-MUC16 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 19; NC_000019.9 (8959516..9092018, complement). Location: 19p13.2
3D Structure
ModBase 3D Structure for Q8WXI7
Species Reactivity
Mouse, Rat
Specificity
Recognizes MUC16.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Concentration
0.5mg/ml (lot specific)
Immunogen
Synthetic peptide corresponding to C-QRHRLAYYLSHLDLRK, from MUC16, at the internal region of the protein (XP_235886.5).
Species sequence homoglogy
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-MUC16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MUC16 antibody
Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Product Categories/Family for anti-MUC16 antibody
Antibodies; Abs to Cancer Markers
Applications Tested/Suitable for anti-MUC16 antibody
Suitable for use in ELSIA. Other applications not tested.
Application Notes for anti-MUC16 antibody
Suitable for use in ELISA.
Dilution: ELISA: 1:1000
Optimal dilutions to be determined by the researcher.
NCBI/Uniprot data below describe general gene information for MUC16. It may not necessarily be applicable to this product.
NCBI Accession #
NP_078966.2
[Other Products]
NCBI GenBank Nucleotide #
NM_024690.2
[Other Products]
UniProt Primary Accession #
Q8WXI7
[Other Products]
UniProt Secondary Accession #
Q6ZQW5; Q96RK2[Other Products]
UniProt Related Accession #
Q8WXI7[Other Products]
NCBI Official Full Name
mucin-16
NCBI Official Synonym Full Names
mucin 16, cell surface associated
NCBI Official Symbol
MUC16??[Similar Products]
NCBI Official Synonym Symbols
CA125
??[Similar Products]
NCBI Protein Information
mucin-16; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125
UniProt Protein Name
Mucin-16
UniProt Synonym Protein Names
Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125
UniProt Gene Name
MUC16??[Similar Products]
UniProt Synonym Gene Names
CA125; MUC-16; CA-125??[Similar Products]
UniProt Entry Name
MUC16_HUMAN
UniProt Comments for MUC16
MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Protein type: Membrane protein, peripheral; Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; integral to membrane; plasma membrane; vesicle
Molecular Function: protein binding
Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification; cell adhesion
Research Articles on MUC16
1. a high CA-125 level correlates significantly with many clinical features of advanced stage, poor prognostic factors, and worse TFS and OS. However, CA-125 is not an independent prognostic factor in patients with chronic lymphocytic leukemia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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