Product Name
8-Oxoguanine DNA Glycosylase (OGG1), Polyclonal Antibody
Full Product Name
Anti - 8-Oxoguanine DNA Glycosylase (OGG1)
Product Synonym Names
8-Oxoguanine DNA Glycosylase (OGG1)
Product Gene Name
anti-OGG1 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 3; NC_000003.11 (9791628..9808353). Location: 3p26.2
3D Structure
ModBase 3D Structure for O15527
Host
Host: Rabbit
Source: Human
Specificity
Recognizes human OGG1.
Purity/Purification
Serum
Form/Format
Serum
Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide, before the addition of glycerol to 40%.
Immunogen
An 18aa peptide close to the N-terminus of human OGG1 (coupled to KLH). Species Sequence Homology: Mouse - 55% (10/18aa); Rat - 38% (7/18aa)
Preparation and Storage
-20 degree C
Other Notes
Small volumes of anti-OGG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-OGG1 antibody
Human 8-Oxoguanine DNA Glycosylase (hOGG1) is involved in the excision of 7, 8-dihydro-8-oxoguanine produced as a result of DNA damage. This gene has been localized on human chromosome 3p25. Several forms of hOGG protein have been cloned differing in lengths (351-424 aa) (1).
Product Categories/Family for anti-OGG1 antibody
Abs to Enzymes
Applications Tested/Suitable for anti-OGG1 antibody
ELISA
Application Notes for anti-OGG1 antibody
ELISA (1:10-50K; using 50-100ng control peptide/well. See O5700-25A.)
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
NCBI/Uniprot data below describe general gene information for OGG1. It may not necessarily be applicable to this product.
UniProt Primary Accession #
O15527
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UniProt Secondary Accession #
O00390; O00670; O00705; O14876; O95488; P78554; Q9BW42; Q9UIK0; Q9UIK1; Q9UIK2; A8K1E3[Other Products]
UniProt Related Accession #
O15527; Q9GZT7; Q9HCR6; Q9HCR8[Other Products]
Molecular Weight
38,782 Da[Similar Products]
NCBI Official Full Name
8-oxoguanine DNA glycosylase
NCBI Official Synonym Full Names
8-oxoguanine DNA glycosylase
NCBI Official Symbol
OGG1??[Similar Products]
NCBI Official Synonym Symbols
HMMH; MUTM; OGH1; HOGG1
??[Similar Products]
NCBI Protein Information
N-glycosylase/DNA lyase; AP lyase; OTTHUMP00000122618; OTTHUMP00000122619; OTTHUMP00000122620; OTTHUMP00000122621; OTTHUMP00000122622; OTTHUMP00000122623; OTTHUMP00000207398; OTTHUMP00000207399; OTTHUMP00000207403; OTTHUMP00000207404; 8-hydroxyguanine DNA glycosylase; DNA-apurinic or apyrimidinic site lyase
UniProt Protein Name
N-glycosylase/DNA lyase
Protein Family
N-glycosylase/DNA lyase
UniProt Gene Name
OGG1??[Similar Products]
UniProt Synonym Gene Names
MMH; MUTM; OGH1??[Similar Products]
UniProt Entry Name
OGG1_HUMAN
Product References and Citations for anti-OGG1 antibody
??1. Aburatani H et al (1997) gene accession # U88620; Radicella JP et al (1997) PNAS 94, 8010-8015; Rosenquist TA et al (1997) PNAS 94, 7429-74342. Kuo FC et al (1997) J Exp Med. (in press).3. Tani M et al (1997) gene accession # AF012912; Prieto-Alamo MJ et al (1997) gene accession # AF029690.
Precautions
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Disclaimer
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